… -genomic approach. In this study, we used an integrated in silico workflow to prospect novel
putative targets using the core genome, a … studies as vaccine targets against this bacterium. …

… core genome data from 63 complete genome sequences of C. difficile strains and employed
a reverse vaccinology approach for the prediction of potential vaccine … of chimeric vaccine …

… this has been used for drug target mining in many pathogens like … genomics approach was
used to identify novel, essential, and human non-homologous drug as well as vaccine targets …

… Alternative treatment options such as vaccines … -genome of A. baumannii followed by
immune-proteomics and reverse vaccinology approaches to identify potential core vaccine targets. …

… In this study, we use the core genes of the C. trachomatis species to search for novel potential
drug and vaccine targets. The conserved-core genes play a vital role in the basic survival …

… view point, that essentiality is not strictly a property of the core genome but that there is a …
important for the discovery of novel potential drug targets. Virulence factors as drug targets …

… targets. In the present study, the core genome data of 56 complete genome sequences of
B… melitensis was retrieved and analyzed based on comparative subtractive genomics and …

… We present vaccine targets against diphtheria caused by Corynebacterium ulcerans. … at
the genomic level of this bacterium in order to suggest proteins as possible vaccine targets. We …

… In this study, the core genome of C. difficile was utilized to identify potential drug and
vaccine targets against C. difficile infections. Subtractive proteomic analysis was performed to …

… coli universal vaccine targets such as FimH and SslE, for … coli core genome that could
represent new vaccine targets, we … can facilitate the identification of exposed targets (33). Among …