Coronary microembolization

G Heusch, R Schulz, M Haude, R Erbel - … molecular and cellular cardiology, 2004 - Elsevier
myocardial injury, as assessed by analysis of CK and troponin T, and better event-free survival
[78]. This beneficial effect is most likely attributable to anti-inflammatory properties of HMG…

[HTML][HTML] A fresh look at coronary microembolization

P Kleinbongard, G Heusch - Nature Reviews Cardiology, 2022 - nature.com
… Increases in levels of biomarkers, such as creatine kinase or troponin (particularly with
high-sensitivity assays), above the normal range reflect myocardial injury but are unspecific and …

Coronary microembolization

A Skyschally, R Erbel, G Heusch - Circulation journal, 2003 - jstage.jst.go.jp
… In summary, the immediate response of coronary blood flow to coronary microembolization
… endothelial damage.That combination of endothelial damage and severe coronary stenosis …

Protective effects and mechanism of curcumin on myocardial injury induced by coronary microembolization

Y Liu, Y Liu, X Huang, J Zhang… - Journal of Cellular …, 2019 - Wiley Online Library
… to myocardial injury and progressive cardiac dysfunction … myocardial injury. The TLR4
pathway-specific inhibitors reduced the CME-induced myocardial injury and improved the cardiac

Coronary microembolization

G Heusch, R Schulz, D Baumgart, M Haude… - … in cardiovascular …, 2001 - Elsevier
coronary blood flow in response to microembolization was even proposed as an early indicator
of myocardial damage … response of coronary blood flow to coronary microembolization is …

Coronary microembolization and microvascular dysfunction

G Heusch, A Skyschally, P Kleinbongard - … journal of cardiology, 2018 - Elsevier
… These periprocedural increases in biomarkers of cardiac injury are mostly transient and
only minor, and they are rarely associated with overt clinical events. While we have become …

[HTML][HTML] Effects of the TLR4/Myd88/NF-κB signaling pathway on NLRP3 inflammasome in coronary microembolization-induced myocardial injury

Q Su, L Li, Y Sun, H Yang, Z Ye, J Zhao - Cellular Physiology and …, 2018 - karger.com
myocardial injury, with … myocardial injury. Blocking the TLR4/MyD88/NF-κB signaling pathway
effectively improved CME-induced myocardial inflammation and reduced myocardial injury

[HTML][HTML] Potential involvement of MiR-30e-3p in myocardial injury induced by coronary microembolization via autophagy activation

X Wang, X Wu, Y Lu, Y Sun, H Zhu, J Liang… - Cellular Physiology and …, 2018 - karger.com
myocardial injury and investigated the possible underlying mechanisms. CME induced
myocardial injury … -3p expression which induced myocardial autophagy inhibition. These findings …

[HTML][HTML] Rosuvastatin protects against coronary microembolization-induced cardiac injury via inhibiting NLRP3 inflammasome activation

AO Chen, Z Chen, Y Zhou, Y Wu, Y Xia, D Lu… - Cell Death & …, 2021 - nature.com
… These results indicated certain cardiac damage following CME. To evaluate the functional
significance of the NLRP3 inflammasome in CME-induced cardiac injury, we used the …

Ligustrazine attenuates myocardial injury induced by coronary microembolization in rats by activating the PI3K/Akt pathway

Q Su, X Lv, Z Ye - Oxidative Medicine and Cellular Longevity, 2019 - Wiley Online Library
… This study hypothesized that ligustrazine attenuates CME-induced myocardial injury in
rats. This study also explored the mechanism underlying this attenuation. Methods. …