Coronary microembolization induces cardiomyocyte apoptosis in swine by activating the LOX-1-dependent mitochondrial pathway and caspase-8-dependent pathway

T Liu, Y Zhou, JY Wang, Q Su… - Journal of …, 2016 - journals.sagepub.com
… Our results indicate that CME induces cardiomyocyte apoptosis in a swine model via the
activation of LOX-1-dependent mitochondrial pathway and caspase-8-dependent pathway. LOX…

TNF‐α‐induced cardiomyocyte apoptosis contributes to cardiac dysfunction after coronary microembolization in mini‐pigs

ZW Chen, JY Qian, JY Ma, SF Chang… - Journal of cellular …, 2014 - Wiley Online Library
… Meanwhile, the average number of apoptotic cardiomyocytes … -α-induced cardiomyocyte
apoptosis is likely involved in cardiaccardiomyocyte apoptosis and improves early cardiac

Coronary Microembolization induces Cardiomyocyte apoptosis through the LOX-1–dependent endoplasmic reticulum stress pathway involving JNK/P38 MAPK

T Liu, Y Zhou, YC Liu, JY Wang, Q Su, ZL Tang… - Canadian Journal of …, 2015 - Elsevier
… -induced apoptosis … in apoptosis. The aim of this study was to investigate whether LOX-1,
ER stress, and MAPKs play a role in cardiomyocyte apoptosis after coronary microembolization

Cardiomyocyte apoptosis and death receptor pathway in a rat model of coronary microembolization

L Li, Q Su, Y Wang, B Su, RX Dai, YG Lu… - Zhonghua xin xue …, 2010 - europepmc.org
Cardiomyocytes apoptosis was significantly increased after coronary microembolization
via activating death receptor apoptotic pathway in this coronary microembolization model. …

Mast cell contributes to cardiomyocyte apoptosis after coronary microembolization

QY Zhang, JB Ge, JZ Chen, JH Zhu… - … of Histochemistry & …, 2006 - journals.sagepub.com
… suggesting that MCs contribute to cardiomyocyte apoptosis in the embolized myocardium
after … progressive cardiomyocyte apoptosis was observed despite early restoration of coronary

[HTML][HTML] Puerarin pretreatment attenuates cardiomyocyte apoptosis induced by coronary microembolization in rats by activating the PI3K/Akt/GSK-3β signaling …

ZQ Chen, Y Zhou, JW Huang, F Chen… - Korean J Physiol …, 2021 - synapse.koreamed.org
… Thus, our CME rat models demonstrated aggravated cardiac dysfunction and cardiomyocyte
apoptosis in the peri-infarct and microinfarct regions, which concur with pathophysiological …

[HTML][HTML] Effect of metoprolol on myocardial apoptosis and caspase-9 activation after coronary microembolization in rats

Q Su, L Li, YC Liu, Y Zhou, YG Lu… - Experimental & Clinical …, 2013 - ncbi.nlm.nih.gov
… on apoptosis following coronary microembolization (original … myocardial apoptosis in control
(1), coronary microembolization (… apoptotic cardiomyocyte nuclei (arrows) are stained brown …

The protective effect of activating Nrf2/HO-1 signaling pathway on cardiomyocyte apoptosis after coronary microembolization in rats

J Liang, L Li, Y Sun, W He, X Wang, Q Su - BMC cardiovascular disorders, 2017 - Springer
apoptosis is closely related to myocardial injury caused by coronary microembolization (…
Nuclear factor erythroid 2-like (Nrf2) has been taken into account as an inhibitor of apoptosis in …

Resveratrol attenuates cardiomyocyte apoptosis in rats induced by coronary microembolization through SIRT1-mediated deacetylation of p53

Q Mao, X Liang, Y Wu, Y Lu - Journal of cardiovascular …, 2019 - journals.sagepub.com
… Therefore, the effect of RES on cardiomyocyte apoptosis and cardiaccardiomyocyte
apoptosis in vivo was developed and tested here. Coronary microembolization resulted in cardiac

[HTML][HTML] Effects of nicorandil on PI3K/Akt signaling pathway and its anti-apoptotic mechanisms in coronary microembolization in rats

Q Su, L Li, J Zhao, Y Sun, H Yang - Oncotarget, 2017 - ncbi.nlm.nih.gov
… and the suppression of cardiomyocyte apoptosis reduces CME-… alleviates cardiomyocyte
apoptosis and improves cardiac … In this study, we found that cardiomyocyte apoptosis was …