[HTML][HTML] Effects of nicorandil on PI3K/Akt signaling pathway and its anti-apoptotic mechanisms in coronary microembolization in rats

Q Su, L Li, J Zhao, Y Sun, H Yang - Oncotarget, 2017 - ncbi.nlm.nih.gov
effects, indicating that they were attributable to the activation of the PI3K/Akt signaling pathway.
In conclusion, nicorandil has significant cardioprotective effects … -PCI use of nicorandil to …

[HTML][HTML] Nicorandil pretreatment inhibits myocardial apoptosis and improves cardiac function after coronary microembolization in rats

WK He, Q Su, JB Liang, XT Wang… - Journal of geriatric …, 2018 - ncbi.nlm.nih.gov
… However, its efficacy of cardioprotection in coronary microembolization (CME) is largely …
whether nicorandil pretreatment could attenuate myocardial apoptosis and improve cardiac

The protective effect of nicorandil on cardiomyocyte apoptosis after coronary microembolization by activating Nrf2/HO-1 signaling pathway in rats

W He, Q Su, J Liang, Y Sun, X Wang, L Li - Biochemical and biophysical …, 2018 - Elsevier
… -apoptotic effect of nicorandil on coronary microembolization … we investigated the effects of
nicorandil pretreatment on … of nicorandil in enhancing CME-induced cardiac dysfunction after …

[HTML][HTML] Nicorandil prevents microvascular dysfunction resulting from PCI in patients with stable angina pectoris: a randomised study

A Hirohata, K Yamamoto, E Hirose… - …, 2014 - eurointervention.pcronline.com
… percutaneous coronary intervention (PCI) by dilating coronary resistance vessels. The aim
of the study was evaluation of the impact of the administration of intravenous nicorandil on …

Nicorandil improves clinical outcomes in patients with stable angina pectoris requiring PCI: a systematic review and meta-analysis of 14 randomized trials

Y Li, H Liu, W Peng, Z Song - Expert Review of Clinical …, 2018 - Taylor & Francis
… Introduction: Clinical trials concerning the effects of nicorandil in stable coronary artery …
clinical outcomes of nicorandil following elective percutaneous coronary intervention (PCI). …

The effect of nicorandil in patients with acute myocardial infarction undergoing percutaneous coronary intervention: a systematic review and meta-analysis

Z Ji, R Zhang, W Lu, G Ma, Y Qu - Irish Journal of Medical Science (1971-), 2020 - Springer
… In rat coronary microembolization (CME) model, nicorandil may play anti-inflammation,
antioxidant, and anti-apoptosis roles through activating the Nrf2/ho-1 signaling pathway to protect …

[HTML][HTML] Role of TLR4/MyD88/NF-κB signaling pathway in coronary microembolization-induced myocardial injury prevented and treated with nicorandil

Q Su, X Lv, Y Sun, Z Ye, B Kong, Z Qin - Biomedicine & Pharmacotherapy, 2018 - Elsevier
effects of nicorandil. Since CME is an important cause of perioperative myocardial injury
during PCI, we believe that nicorandil may … Hence, this study evaluated the effects of nicorandil

Nicorandil protects against coronary microembolization-induced myocardial injury by suppressing cardiomyocyte pyroptosis via the AMPK/TXNIP/NLRP3 signaling …

Y Liu, J Shu, T Liu, J Xie, T Li, H Li, L Li - European journal of pharmacology, 2022 - Elsevier
… , but the cardioprotective effects of nicorandil beyond anti-… present study investigated the
effect of nicorandil on CME-… indicated that the protective effects of nicorandil in CME likely …

Efficacy of nicorandil on the prevention of contrast-induced nephropathy in patients with coronary heart disease undergoing percutaneous coronary intervention

X Zhang, S Yang, P Zhang, N Fu - Coronary Artery Disease, 2020 - journals.lww.com
… study was to explore the effect of nicorandil on the incidence of contrast-induced nephropathy
in patients with coronary heart disease undergoing percutaneous coronary intervention. …

[HTML][HTML] The effect on periprocedural myocardial infarction of intra-coronary nicorandil prior to percutaneous coronary intervention in stable and unstable angina

J Hwang, HC Lee, BW Kim, MJ Yang, JS Park… - Journal of …, 2013 - Elsevier
… In the nicorandil group, 4 mg of intra-coronary nicorandil was infused prior to PCI (2 mg
before ballooning and 2 mg before stenting). The control group was treated without nicorandil. …