Breviscapine pretreatment inhibits myocardial inflammation and apoptosis in rats after coronary microembolization by activating the PI3K/Akt/GSK-signaling …

ZQ Chen, Y Zhou, F Chen, JW Huang… - Drug design …, 2021 - Taylor & Francis
Coronary microembolization (CME) can lead to slow or even lack of reflow in the myocardium
and occurs due to percutaneous coronary intervention (PCI) for acute coronary syndrome …

Resveratrol pretreatment inhibits myocardial apoptosis in rats following coronary microembolization via inducing the PI3K/Akt/GSK-signaling cascade

T Li, Z Chen, Y Zhou, H Li, J Xie, L Li - Drug Design, Development …, 2021 - Taylor & Francis
Coronary microembolization (CME) commonly occurs during thrombolytic therapy or
percutaneous coronary intervention. CME is caused by atherosclerotic unstable plaques rupturing …

[HTML][HTML] Puerarin pretreatment attenuates cardiomyocyte apoptosis induced by coronary microembolization in rats by activating the PI3K/Akt/GSK-signaling …

ZQ Chen, Y Zhou, JW Huang, F Chen… - Korean J Physiol …, 2021 - synapse.koreamed.org
Coronary microembolization (CME) is associated with cardiomyocyte apoptosis and cardiac
… could alleviate cardiomyocyte apoptosis and improve cardiac function following CME. The …

Upregulation of miR-29b-3p alleviates coronary microembolization-induced myocardial injury via regulating BMF and GSK-

Z Qin, X Wang, Y Zhou, J Zheng, H Li, L Li - Apoptosis, 2023 - Springer
Coronary microembolization (CME) is an intractable complication results from acute coronary
… CME-induced myocardial apoptosis was associated with progressive cardiac contractile …

Dynamic changes and the relationship between cardiac function damage and glycogen synthase kinase-3 β expression induced by coronary microembolization in …

B Kong, Z Qin, J Zheng, M Long - Cardiology Plus, 2019 - journals.lww.com
… In summary, GSK-3 β is involved in the damage to cardiac function induced by CME and
shows obvious time variation, which may be achieved by regulating the expression of …

Alprostadil injection attenuates coronary microembolization-induced myocardial injury through GSK-/Nrf2/HO-1 signaling-mediated apoptosis inhibition

Z Qin, B Kong, J Zheng, X Wang, L Li - Drug design, development …, 2020 - Taylor & Francis
Objective Coronary microembolization (CME) results in progressive contractile dysfunction
associated with cardiomyocyte apoptosis. Alprostadil injection improves microcirculation, …

A fresh look at coronary microembolization

P Kleinbongard, G Heusch - Nature Reviews Cardiology, 2022 - nature.com
… in the presentation of acute coronary syndromes. An associated … We propose that coronary
microembolization is a decisive … and mechanisms of coronary microembolization and discuss …

[HTML][HTML] … synthase kinase -mitochondrial permeability transition pore pathway in rat hearts subjected to sodium laurate-induced coronary microembolization

H Zhu, Y Ding, X Xu, M Li, Y Fang, B Gao… - American journal of …, 2017 - ncbi.nlm.nih.gov
… mtDNA copy number and formation of microemboli. Adjusting dosages of PGE1 might …
GSK- in this study. Hence, we cannot exclude the possibility that our findings regarding GSK-

The interaction of coronary microembolization and ischemic preconditioning: a third window of cardioprotection through TNF-alpha

P Heusch, A Skyschally, K Leineweber… - Archives of Medical …, 2007 - termedia.pl
ams 2 2007.qxp Page 1 The interaction of coronary microembolization and ischemic
preconditioning: A third window of cardioprotection through TNF-alpha Philipp Heusch1, Andreas …

Aloperine activates the PI3K/Akt pathway and protects against coronary microembolisation-induced myocardial injury in rats

Q Mao, F Guo, X Liang, Y Wu, Y Lu - Pharmacology, 2019 - karger.com
… Background: Coronary microembolisation (CME)-induced myocardial apoptosis is a key
factor in progressive cardiac dysfunction. Aloperine (ALO) plays a protective role in the …