Differential impact of stress and environmental enrichment on corticolimbic circuits

MA Smail, BL Smith, N Nawreen, JP Herman - … biochemistry and behavior, 2020 - Elsevier
… One of the most promising of these alternatives is environmental enrichment (EE). In rodents…
neurotrophic growth factors, effects that vary by type of enrichment, age, and sex. To add to …

[HTML][HTML] Environmental enrichment and gut inflammation modify stress-induced c-Fos expression in the mouse corticolimbic system

F Reichmann, E Painsipp, P Holzer - PloS one, 2013 - journals.plos.org
corticolimbic system and whether this stress response is altered by gastritis or colitis. Male
C67BL/6N mice were housed under standard or enriched environmentcorticolimbic system, …

[HTML][HTML] Impact of environmental enrichment on the GABAergic neurons and glucocorticoid receptors in the hippocampus and nucleus accumbens of Wistar rats: Pro …

A Begega, CI Jove, M López, RD Moreno - Brain Research Bulletin, 2023 - Elsevier
… This regulation involves limbic system regions such as the … lead to alterations in this system
that produce behavioral deficits … The GABAergic system is also involved in the regulation of …

[HTML][HTML] Early-life short-term environmental enrichment counteracts the effects of stress on anxiety-like behavior, brain-derived neurotrophic factor and nuclear …

A Hegde, S Suresh, R Mitra - Scientific reports, 2020 - nature.com
system 32,44 , and this effect can be effectively reversed by providing environmental enrichment
… In contrast to these earlier studies, stress and enrichment were concomitant during early …

Brief environmental enrichment elicits metaplasticity on the insular cortex in vivo and reduces the strength of conditioned taste aversion

B Gutiérrez-Vera, SE Reyes-García… - Neurobiology of Learning …, 2023 - Elsevier
… In the present study, we show that exposure to a brief environmental enrichment reduces
the strength of aversion in the CTA task, presumably by the modification of synaptic plasticity in …

[HTML][HTML] Environmental enrichment induces behavioural disturbances in neuropeptide Y knockout mice

F Reichmann, V Wegerer, P Jain, R Mayerhofer… - Scientific reports, 2016 - nature.com
Environmental enrichment (EE) refers to the provision of a complex and stimulating housing
… The NPY system could thus be a target for “enviromimetics”, therapeutics which reproduce …

Effects of acute or chronic environmental enrichment on regional Fos protein expression following sucrose cue-reactivity testing in rats

JW Grimm, JL Barnes, J Koerber, E Glueck… - Brain Structure and …, 2016 - Springer
… following exposure of rodents to environmental enrichment (EE). … Fos expression in several
corticolimbic brain regions. … circuitry tracks and adapts to the current perceived value of the …

How environmental enrichment balances out neuroinflammation in chronic pain and comorbid depression and anxiety disorders

LF Kimura, LS Novaes, G Picolo… - British Journal of …, 2022 - Wiley Online Library
system and activation of β 1 - and β 2 -adrenoceptors. Accordingly, the maintenance of
the integrity and homeostasis of the norepinephrine system by environmental enrichment

Environmental enrichment prevents stress-induced epigenetic changes in the expression of glucocorticoid receptor and corticotrophin releasing hormone in the …

A Orock, T Louwies, CO Ligon, E Mohammadi… - Experimental …, 2021 - Elsevier
… If, in the current study, EE engaged the endogenous opioid system, it may have
counterbalanced the detrimental effects of chronic WAS. Some studies have shown that removing …

Neurotransmitters and prefrontal cortex–limbic system interactions: implications for plasticity and psychiatric disorders

AD Arco, F Mora - Journal of neural transmission, 2009 - Springer
… to be a key factor in the corticolimbic hyperactivity associated with psychiatric disorders such
as … activity of the acetylcholine system, but not that of the dopamine system, in the NAc is …