KRAS mutation testing of tumours in adults with metastatic colorectal cancer: a systematic review and cost-effectiveness analysis
M Westwood, ADI Asselt, B Ramaekers, P Whiting… - 2014 - repub.eur.nl
… These vary in the specific mutations that they detect, the amount of mutation they detect, the
… cost. Objectives: To compare the performance and cost-effectiveness of KRAS mutation tests …
… cost. Objectives: To compare the performance and cost-effectiveness of KRAS mutation tests …
[HTML][HTML] Testing for BRCA1 mutations: a cost-effectiveness analysis
C Sevilla, JP Moatti, C Julian-Reynier… - European Journal of …, 2002 - nature.com
… strategy, ie, that corresponding to the lowest cost per mutation detected, was found to be
a … Our results on genetic testing for breast cancer show that DS is not the most cost-effective …
a … Our results on genetic testing for breast cancer show that DS is not the most cost-effective …
Mutation versus all-uses: An empirical evaluation of cost, strength and effectiveness
… portion of the computational cost of mutation testing is incurred in executing mutants against
test cases, this cost can be reduced significantly by reducing the number of mutants to be …
test cases, this cost can be reduced significantly by reducing the number of mutants to be …
A cost-effectiveness analysis of multigene testing for all patients with breast cancer
L Sun, A Brentnall, S Patel, DSM Buist… - JAMA …, 2019 - jamanetwork.com
… cost-effective for unselected genetic testing; from the societal perspective, 1% simulations
are cost-effective for testing … % simulations are cost-effective for unselected genetic testing. C …
are cost-effective for testing … % simulations are cost-effective for unselected genetic testing. C …
[HTML][HTML] Cost-effectiveness analysis of EGFR mutation testing and gefitinib as first-line therapy for non-small cell lung cancer
Y Narita, Y Matsushima, T Shiroiwa, K Chiba… - Lung Cancer, 2015 - Elsevier
… ‘EGFR testing strategy’, in which EGFR mutation testing was … mutations received gefitinib
while those without mutations … ‘no-testing strategy,’ in which genetic testing was not conducted …
while those without mutations … ‘no-testing strategy,’ in which genetic testing was not conducted …
Cost-effectiveness of population-based BRCA1, BRCA2, RAD51C, RAD51D, BRIP1, PALB2 mutation testing in unselected general population women
R Manchanda, S Patel, VS Gordeev… - JNCI: Journal of the …, 2018 - academic.oup.com
… Given the effective options available for OC … cost-effective at 4% to 5% OC risk (15,16). This
enables clinical utility and supports implementation of clinical testing for these gene mutations…
enables clinical utility and supports implementation of clinical testing for these gene mutations…
[HTML][HTML] … kinase (EGFR-TK) mutation testing in adults with locally advanced or metastatic non-small cell lung cancer: a systematic review and cost-effectiveness …
M Westwood, M Joore, P Whiting… - Health Technology …, 2014 - ncbi.nlm.nih.gov
… To compare the performance and cost-effectiveness of EGFR-TK mutation tests used to
identify previously untreated adults with locally advanced or metastatic NSCLC, who may benefit …
identify previously untreated adults with locally advanced or metastatic NSCLC, who may benefit …
Cost‐effectiveness of epidermal growth factor receptor mutation testing and first‐line treatment with gefitinib for patients with advanced adenocarcinoma of the lung
… determine the cost-effectiveness of EGFR mutation testing and first-line treatment with gefitinib
followed by second-line chemotherapy for patients who have activating EGFR mutations, …
followed by second-line chemotherapy for patients who have activating EGFR mutations, …
Reducing the cost of mutation testing: An empirical study
… criteria are examined for their cost effectiveness and strength compared with mutation …
alternate mutations may serve as cost-effective alternatives to mutation testing in applications that …
alternate mutations may serve as cost-effective alternatives to mutation testing in applications that …
Cost effectiveness of population based BRCA1 founder mutation testing in Sephardi Jewish women
S Patel, R Legood, DG Evans, C Turnbull… - American journal of …, 2018 - Elsevier
… Our study shows population testing for BRCA1 mutations in SJ is extremely cost effective
compared with traditional FH-based testing and supports a paradigm change to population-…
compared with traditional FH-based testing and supports a paradigm change to population-…
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