Impact of low dose tocilizumab on mortality rate in patients with COVID-19 related pneumonia

R Capra, N De Rossi, F Mattioli, G Romanelli… - European journal of …, 2020 - Elsevier
… This study aims to evaluate the efficacy of tocilizumab (in terms of mortality rates) in
COVID-19 patients with pneumonia and uses posology ranging from 8 mg/kg up to 800 mg (possibly …

COVIDOSE: a phase II clinical trial of low‐dose tocilizumab in the treatment of noncritical COVID19 pneumonia

GW Strohbehn, BL Heiss, SJ Rouhani… - Clinical …, 2021 - Wiley Online Library
… to administer low-dose tocilizumab to hospitalized patients with COVID-19. We present
the … evidence of low-dose tocilizumab activity in hospitalized patients with COVID-19–associated …

COVIDOSE: Low-dose tocilizumab in the treatment of Covid-19

GW Strohbehn, BL Heiss, SJ Rouhani, JA Trujillo, J Yu… - medRxiv, 2020 - medrxiv.org
… trial of low-dose tocilizumab in hospitalized adult patients with Covid-19, … Dose cohorts were
determined by a trial Operations … A range of doses from 40 to 200 mg (low-dose tocilizumab) …

[HTML][HTML] Early use of low dose tocilizumab in patients with COVID-19: a retrospective cohort study with a complete follow-up

N De Rossi, C Scarpazza, C Filippini, C Cordioli… - …, 2020 - thelancet.com
… paper, we describe 158 patients with COVID-19, ninety of whom were treated early in the
disease course with single - low dose of tocilizumab. Our a priori hypothesis was twofold. First, …

[HTML][HTML] Rationale and evidence on the use of tocilizumab in COVID-19: a systematic review

A Cortegiani, M Ippolito, M Greco, V Granone, A Protti… - Pulmonology, 2021 - Elsevier
… Single-centre nonrandomized observational study (USA) ICU patients with critical COVID-19
(n = 60) 400 mg flat dosing of tocilizumab with possible redosing based on clinical …

Tocilizumab for treatment patients with COVID-19: recommended medication for novel disease

H Samaee, M Mohsenzadegan, S Ala… - International …, 2020 - Elsevier
… [33] In a retrospective study conducted by Alattar and colleagues in Qatar, 25 patients with
COVID-19 received one to three median doses 4.8 mg/kg. Result of this study showed that …

Tocilizumab for severe COVID-19: a systematic review and meta-analysis

SH Lan, CC Lai, HT Huang, SP Chang, LC Lu… - International journal of …, 2020 - Elsevier
… and ARDS requiring ventilatory support in Brescia (Italy), in which tocilizumab was administered
at a dosage of 8 mg/kg using two consecutive intravenous infusions 12 h apart, and an …

[HTML][HTML] Rapid and impressive response to a combined treatment with single-dose tocilizumab and NIV in a patient with COVID-19 pneumonia/ARDS

M Cascella, I Mauro, E De Blasio, A Crispo… - Medicina, 2020 - mdpi.com
Treatment of acute respiratory distress syndrome (ARDS) due to COVID-19 pneumonia (…
antibody tocilizumab (TCZ). We reported the case of a 54-year-old 100 kg male COVID-19

Tocilizumab treatment in COVID19: a single center experience

P Luo, Y Liu, L Qiu, X Liu, D Liu… - Journal of medical …, 2020 - Wiley Online Library
doses of TCZ is recommended for critically ill COVID-19 … -IL-6 receptor antibody TCZ in
COVID-19 patients is based on our … The present study suggested that a single dose of TCZ seems …

[HTML][HTML] Low-dose subcutaneous tocilizumab to prevent disease progression in patients with moderate COVID-19 pneumonia and hyperinflammation

N Potere, M Di Nisio, G Rizzo, M La Vella… - International Journal of …, 2020 - Elsevier
… efficacy profile of low-dose tocilizumab (TCZ), to prevent disease progression, subcutaneously
administered to patients with moderate COVID-19 pneumonia and hyperinflammation. …