Immune reactivity during COVID-19: Implications for treatment

C Napoli, G Benincasa, C Criscuolo, M Faenza… - Immunology letters, 2021 - Elsevier
… value in COVID-19 and the basis of immunological reactivity during COVID-19, with a
focus on ongoing clinical trials evaluating immune targets as possible therapeutic strategies. …

[HTML][HTML] COVID-19 and the immune system

J Paces, Z Strizova, S Daniel, J Cerny - Physiological research, 2020 - ncbi.nlm.nih.gov
… -immune system interplay. Most of the current knowledge regarding the mechanisms of immune
responses in COVID-19 … discuss the immunological features of COVID-19 with the aim to …

The immune response and immunopathology of COVID-19

E Mortaz, P Tabarsi, M Varahram, G Folkerts… - Frontiers in …, 2020 - frontiersin.org
… The reason for the resistance of children to COVID-19 is also unclear. However, it seems
that their immune reactivity is lower than in adults and that although infants are susceptible to …

Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity

…, MGH COVID-19 Collection & Processing Team 16‡… - Science, 2020 - science.org
… 232 COVID-19 patients and 190 pre–COVID-19 era controls against the original VirScan and
supplemental coronavirus … To measure immune responses to SARS-CoV-2, we compared …

Immune responses during COVID-19 infection

C Melenotte, A Silvin, AG Goubet, I Lahmar… - …, 2020 - Taylor & Francis
… The unpredictability of coronavirus disease-19 (COVID-19) … risk factors for severe COVID-19,
insufficient diagnostic tools … While protective humoral and cellular immune responses are …

Adaptive immunity and the risk of autoreactivity in COVID-19

R Moody, K Wilson, KL Flanagan… - International journal of …, 2021 - mdpi.com
… Another association between SARS-CoV-1 and autoimmune diseases has been identified
through immune cross-reactivity [42]. Patients with autoimmune diseases (SLE, Sjögren’s …

[HTML][HTML] COVID-19 immune signatures reveal stable antiviral T cell function despite declining humoral responses

A Bonifacius, S Tischer-Zimmermann, AC Dragon… - Immunity, 2021 - cell.com
Immune responses toward huCoV in RCs with mild disease and strong cellular SARS-CoV-2
T cell reactivity imply a protective role of pre-existing immunity against huCoV. …

Integrated immune dynamics define correlates of COVID-19 severity and antibody responses

M Koutsakos, LC Rowntree, L Hensen, BY Chua… - Cell Reports …, 2021 - cell.com
… Strikingly, intensive care unit (ICU) patients with severe COVID-19COVID-19 patients and
integrate key cellular pathways of complex immune networks underpinning severe COVID-19, …

Cross-immunity between respiratory coronaviruses may limit COVID-19 fatalities

A Yaqinuddin - Medical hypotheses, 2020 - Elsevier
COVID-19 in locations where SARS-like infections have been prevalent is due to partial
immunity conferred from cross reactivity … assessed in convalescent COVID-19 patients with mild, …

A dynamic COVID-19 immune signature includes associations with poor prognosis

AG Laing, A Lorenc, I Del Molino Del Barrio, A Das… - Nature medicine, 2020 - nature.com
… peripheral blood immune signature across 63 hospital-treated patients with COVID-19 who
… Hence, contingent upon independent validation in other COVID-19 cohorts, individual traits …