COVID-19: drug targets and potential treatments

C Gil, T Ginex, I Maestro, V Nozal… - Journal of medicinal …, 2020 - ACS Publications
… (154) Recently, baricitinib, a potent AAK1 and GAK inhibitor, has been proposed as an
effective therapy for COVID-19, reducing the viral entry, although no experimental work has been …

On the inhibition of COVID-19 protease by Indian herbal plants: an in silico investigation

AK Srivastava, A Kumar, N Misra - arXiv preprint arXiv:2004.03411, 2020 - arxiv.org
inhibition potential against COVID-19 protease. Thus, our docking analyses suggest that the
COVID-19 protease (6LU7) can be inhibited … on the inhibition of COVID-19 protease by the …

In silico detection of inhibitor potential of Passiflora compounds against SARS-Cov-2 (Covid-19) main protease by using molecular docking and dynamic analyses

S Yalçın, S Yalçınkaya, F Ercan - Journal of Molecular Structure, 2021 - Elsevier
… a suitable target for identifying potential drug substances. We also … drug potential of Passiflora
components against COVID-19 … drug potential of Passiflora components against COVID-19

A review of potential suggested drugs for coronavirus disease (COVID-19) treatment

P Tarighi, S Eftekhari, M Chizari, M Sabernavaei… - European Journal of …, 2021 - Elsevier
… is a potent inhibitor of cell membrane fusion resulting from covid-19 spike glycoprotein based
on an in-vitro study. So they suggested subsequent and more evaluation of the potential of …

Natural products for COVID19 prevention and treatment regarding to previous coronavirus infections and novel studies

M Boozari, H Hosseinzadeh - Phytotherapy Research, 2021 - Wiley Online Library
… Another study exhibit the potential in vitro inhibitory activity of lycorine against … for SARS
and MERS the potential herbal treatments for COVID-19 are suggested. Natural products can …

Computationally approached inhibition potential of Tinospora cordifolia towards COVID-19 targets

S Jena, P Munusami, B Mm, K Chanda - Virusdisease, 2021 - Springer
… The investigations are progressing towards COVID-19 therapeutics. Among the various …
are investigated as potential drug candidates for COVID-19. The inhibition potential of the …

[PDF][PDF] A drug repurposing approach towards elucidating the potential of flavonoids as COVID-19 spike protein inhibitors

P Pandey, F Khan, AK Rana, Y Srivastava… - … Res. Appl. Chem, 2021 - researchgate.net
… of COVID-19. Our findings clearly state that all the phytocompounds have better inhibitory
potential (binding affinity) against COVID-19 in comparison to the standard drugs. However, …

[PDF][PDF] Inhibitory potential of dietary phytocompounds of nigella sativa against key targets of novel coronavirus (COVID-19)

P Pandey, F Khan, A Mazumder… - Indian J. Pharm …, 2021 - pdfs.semanticscholar.org
… phytocompound for COVID-19 treatment, we have chosen eight potential phytocompounds
from Nigella sativa which have displayed momentous inhibitory potential against numerous …

Discovery of a novel inhibitor of coronavirus 3CL protease for the potential treatment of COVID-19

B Boras, RM Jones, BJ Anson, D Arenson… - BioRxiv, 2020 - biorxiv.org
… of this compound as a potential COVID-19 treatment. … we identified a potential small molecule
protease inhibitor (PF-… as a potential SARS-CoV-2 3CLpro inhibitor for the treatment of …

PI3Kδ inhibition as a potential therapeutic target in COVID-19

G Palma, T Pasqua, G Silvestri, C Rocca… - Frontiers in …, 2020 - frontiersin.org
… with an antiviral in the treatment of COVID-19 positive patients is underway (21). … COVID-19,
this review aims to evaluate an alternative therapeutic strategy by using the PI3Kδ inhibitor