Lung protection by cathepsin C inhibition: A new hope for COVID-19 and ARDS? Miniperspective

B Korkmaz, A Lesner, S Marchand-Adam… - Journal of Medicinal …, 2020 - ACS Publications
COVID-19 is the third emergence of a coronavirus in less than 20 years. Its clinical spectrum
… of COVID-19 patients, is a type of respiratory failure characterized by acute lung injury and …

[HTML][HTML] Lung protection vs. infection resolution: interleukin 10 suspected of double-dealing in COVID-19

HA Lindner, SY Velasquez, M Thiel… - Frontiers in …, 2021 - frontiersin.org
lung protection and virus replication not only in the pre-clinical phase, but that this cytokine
may still be double-dealing in the critical phase of COVID-19 … factor in lung protection and the …

Lungs as target of COVID-19 infection: Protective common molecular mechanisms of vitamin D and melatonin as a new potential synergistic treatment

VMM Giménez, F Inserra, CD Tajer, J Mariani, L Ferder… - Life sciences, 2020 - Elsevier
… melatonin and vitamin D as a new potential synergistic treatment in COVID-19 lung infection:
The cross-talk between melatonin-RAS-vitamin D, a rational protagonist triad in COVID-19? …

[HTML][HTML] COVID-19 infection: the perspectives on immune responses

Y Shi, Y Wang, C Shao, J Huang, J Gan… - Cell Death & …, 2020 - nature.com
… : the first immune defense-based protective phase and the second inflammation-driven …
Since Vitamin B3 is highly lung protective, it should be used as soon as coughing begins. …

Will we see protection or reinfection in COVID-19?

M Ota - Nature Reviews Immunology, 2020 - nature.com
… that patients who recover from COVID-19 may be at risk of … , lungs and gut, with
histopathological evidence of lung … not show any signs of COVID-19 disease recurrence. This …

Management of COVID-19 respiratory distress

JJ Marini, L Gattinoni - Jama, 2020 - jamanetwork.com
… When confronting such an unfamiliar and rapidly evolving environment, only certain aspects
of well-accepted lung-protective approaches to ARDS remain rational at these different …

[HTML][HTML] Lung surfactant for pulmonary barrier restoration in patients with COVID-19 pneumonia

U Mirastschijski, R Dembinski, K Maedler - Frontiers in medicine, 2020 - frontiersin.org
lung protective efficacy and the today's urgent need for lung … of COVID-19 pneumonia
patients on ICUs with natural lung … reaction found in lung autopsies of COVID-19 patients (22). …

[HTML][HTML] Combating COVID-19: MVA vector vaccines applied to the respiratory tract as promising approach toward protective immunity in the lung

R Förster, H Fleige, G Sutter - Frontiers in immunology, 2020 - frontiersin.org
… The lung is the vital target organ of coronavirus disease 2019 (COVID-19) caused by
infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In the majority of …

Efficacy of losartan in hospitalized patients with COVID-19–induced lung injury: a randomized clinical trial

…, CJ Tignanelli, ARBBL Protective… - JAMA network …, 2022 - jamanetwork.com
… of COVID-19–induced acute lung injury, angiotensin receptor blockade with maximal dose
losartan did not reduce lung … did not reduce lung injury in patients with COVID-19 and raised …

[HTML][HTML] Respiratory support in COVID-19 patients, with a focus on resource-limited settings

AM Dondorp, M Hayat, D Aryal, A Beane… - The American journal …, 2020 - ncbi.nlm.nih.gov
… In these patients, lung protective ventilation is essential. Severe pneumonia in COVID-19
differs … very high case fatality rate of more than 50% in invasively ventilated COVID-19 patients. …