[HTML][HTML] Severe COVID-19: NLRP3 inflammasome dysregulated
DF Van den Berg, AA Te Velde - Frontiers in immunology, 2020 - frontiersin.org
… The data presented in this overview suggest that the NLRP3 inflammasome with its
downstream pathways is an attractive target for therapy of COVID-19 with (severe) pathology in …
downstream pathways is an attractive target for therapy of COVID-19 with (severe) pathology in …
The NLRP3 inflammasome and COVID-19: Activation, pathogenesis and therapeutic strategies
N Zhao, B Di, L Xu - Cytokine & growth factor reviews, 2021 - Elsevier
… NLRP3 inflammasome in COVID-19, this review describes the possible pathways of NLRP3
inflammasome … , the role of the NLRP3 inflammasome in the pathogenesis of COVID-19 and …
inflammasome … , the role of the NLRP3 inflammasome in the pathogenesis of COVID-19 and …
[HTML][HTML] Targeting the NLRP3 inflammasome in severe COVID-19
TL Freeman, TH Swartz - Frontiers in immunology, 2020 - frontiersin.org
… -containing 3 (NLRP3) inflammasome pathway and … COVID-19 and NLRP3 activation
and describe an important role in targeting this pathway for the treatment of severe COVID-19…
and describe an important role in targeting this pathway for the treatment of severe COVID-19…
[HTML][HTML] Novel coronavirus-induced NLRP3 inflammasome activation: a potential drug target in the treatment of COVID-19
A Shah - Frontiers in immunology, 2020 - frontiersin.org
… NLRP3 inflammasome appears to be a potential drug target in the treatment of coronavirus
disease 2019 (COVID-19… This manuscript highlights the importance of NLRP3 inflammasome …
disease 2019 (COVID-19… This manuscript highlights the importance of NLRP3 inflammasome …
The inflammasome in times of COVID-19
… However, ASC knockouts significantly decreased the levels of IL-1β (89), pointing to the
possibility that even if the NLRP3 inflammasome is blocked, other inflammasomes that require …
possibility that even if the NLRP3 inflammasome is blocked, other inflammasomes that require …
[HTML][HTML] Common NLRP3 inflammasome inhibitors and Covid-19: divide and conquer
… In Covid-19, high neutrophil recruitment is correlated with disease severity; thereby
colchicine may reduce Covid-19 severity through inhibition of NLRP3 inflammasome, neutrophil …
colchicine may reduce Covid-19 severity through inhibition of NLRP3 inflammasome, neutrophil …
NLRP3 inflammasome: the stormy link between obesity and COVID-19
A Lopez-Reyes, C Martinez-Armenta… - Frontiers in …, 2020 - frontiersin.org
… clinical symptoms in COVID-19, we aimed to suggest the possible role of NLRP3
inflammasome as a link between obesity and the increased risk for a severe COVID-19 outcome. …
inflammasome as a link between obesity and the increased risk for a severe COVID-19 outcome. …
[HTML][HTML] NLRP3 inflammasome activation in COVID-19: an interlink between risk factors and disease severity
… In this review, to delineate the interlink between NLRP3 inflammasome activation and
underlying conditions of COVID-19 severity, we focused on the mechanisms of NLRP3 mediated …
underlying conditions of COVID-19 severity, we focused on the mechanisms of NLRP3 mediated …
NLRP3 inflammasome and interleukin-1 contributions to COVID-19-associated coagulopathy and immunothrombosis
N Potere, E Garrad, Y Kanthi, M Di Nisio… - Cardiovascular …, 2023 - academic.oup.com
… COVID-19. We also summarize current efforts to target the NLRP3 inflammasome pathway in
COVID-19… and the therapeutic potential that inflammasome-targeted strategies may provide …
COVID-19… and the therapeutic potential that inflammasome-targeted strategies may provide …
Specific inhibition of the NLRP3 inflammasome suppresses immune overactivation and alleviates COVID-19 like pathology in mice
J Zeng, X Xie, XL Feng, L Xu, JB Han, D Yu, QC Zou… - …, 2022 - thelancet.com
… The NLRP3 inflammasome is activated upon SARS-CoV-2 infection and … with COVID-19
severity. However, the processes by which the NLRP3 inflammasome is involved in COVID-19 …
severity. However, the processes by which the NLRP3 inflammasome is involved in COVID-19 …
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