… termed coronavirus disease of 2019 (COVID-19). Here, we investigate … between plasma
ACE2 and outcome of COVID-19. … plasma ACE2 is potentially valuable in predicting COVID-19 …

… Levels of the truncated ACE2 species served … plasma ACE2 species are altered in patients
with COVID‐19 and these changes normalize during the recovery phase. Alterations in ACE2 …

… activity levels are increased in those with more severe COVID-19 infection… plasma ACE2
activity in the setting of COVID-19 are unknown, we have reported that increased plasma ACE2 …

… COVID-19 or influenza compared with uninfected control subjects (5). Hypothesizing that
ACE2 … we aimed at assessing plasma ACE2 in patients with COVID-19 of variable severity over …

… , while plasma isolated from COVID-19 recovered patients … all around the world to treat
COVID-19 patients. For this, we … and the convalescent plasma in the COVID-19 treatment. The …

… COVID-19 pandemic is caused by the novel coronavirus SARS-CoV-2. Angiotensin-converting
enzyme 2 (ACE2) is … expressed in the heart, kidneys, and lungs and shed into the plasma. …

… We speculate that the elevation of sACE2 levels in the plasma is partially attributed to
virus-induced shedding. In parallel, a higher concentration of sACE2 is followed by increased virus-…

… Secondly, plasma ACE2 arises from shedding of mACE2 via ADAM-17 protease induced
by … possibly accentuating COVID-19 risks [4]. Hence, increased shedding of ACE2 should …

… of ACE2 expression and Ang II plasma concentration in SARS-… COVID-19 patients express
less ACE2 mRNA than cells from healthy volunteers. At the level of circulating cells, this ACE2 …

… men exhibited higher plasma concentrations of sACE2 … COVID-19 severity. Although this
was not the objective of our studies we found no association of plasma levels of soluble ACE2 …