Heparin-binding protein levels correlate with aggravation and multiorgan damage in severe COVID-19

M Xue, Y Zeng, HQ Qu, T Zhang, N Li… - ERJ Open …, 2021 - Eur Respiratory Soc
… In line with the purpose of this study on HBP and COVID-19 … the potential pathological roles
of HBP in severe COVID-19, its value as a therapeutic target is highlighted [62], eg by heparin

Therapeutic anticoagulation with heparin in noncritically ill patients with Covid-19

ATTACC, ACTIV-4a, and REMAP-CAP … - New England Journal …, 2021 - Mass Medical Soc
Background Thrombosis and inflammation may contribute to the risk of death and
complications among patients with coronavirus disease 2019 (Covid-19). We hypothesized that …

Prophylactic or therapeutic doses of heparins for COVID-19 infection? A retrospective study

F Bolzetta, M Maselli, M Formilan, F Busonera… - Aging Clinical and …, 2021 - Springer
… ’ dosages and mortality, we used a Cox’s regression analysis, adjusted for potential
confounders. Confounders (ie age, sex, and presence of obesity, diabetes, cancer, COPD, dementia…

Structural features and PF4 functions that occur in heparin-induced thrombocytopenia (HIT) complicated by COVID-19

Z Cai, MI Greene, Z Zhu, H Zhang - Antibodies, 2020 - mdpi.com
… detected in severe patients and heparin-induced thrombocytopenia (… COVID-19 patients
define a potential therapeutic option of using blocking antibodies in the treatment of COVID-19

Not Just Anticoagulation—New and Old Applications of Heparin

L Zang, H Zhu, K Wang, Y Liu, F Yu, W Zhao - Molecules, 2022 - mdpi.com
… This review focused on the new and old applications of heparin and discussed the potential
… thromboembolism rates in COVID-19 increase the possibility that heparin may benefit the …

[PDF][PDF] Potential role of lactoferrin and heparin in COVID-19: A review

B Hoxha, A Hodaj - Eur. Sci. J. ESJ, 2021 - researchgate.net
… evidence the potential role of lactoferrin (LF) and heparin in coronavirus disease 2019 (COVID-19)…
Heparin and LF could reduce viral entry by preventing the attachment of severe acute …

[PDF][PDF] Clinical observations of low molecular weight heparin in relieving inflammation in COVID-19 patients: A retrospective cohort study

C Shi, C Wang, H Wang, C Yang, F Cai, F Zeng… - medrxiv, 2020 - scholar.archive.org
… the lymphocytes (LYM%)of patients and has the potential for treatment of COVID-19. … of
patients with COVID-19 to investigate the anti-inflammatory effects of heparin and delay disease …

Heparin: A simplistic repurposing to prevent SARS-CoV-2 transmission in light of its in-vitro nanomolar efficacy

Y Gupta, D Maciorowski, SE Zak, CV Kulkarni… - International Journal of …, 2021 - Elsevier
… Searching for repurposable drugs with potential targets among the … COVID-19, heparin
emerged as an interesting compound to pursue. The use of heparin for treating severe COVID-19-…

[PDF][PDF] Therapeutic Anticoagulation with Heparin in Patients with Covid-19.

AV Sterpetti - New England Journal of Medicine, 2021 - escholarship.org
… No other potential conflict of interest relevant to this letter … for Covid-19, therapeutic-dose
anticoagulation with heparin was … dose anticoagulation with heparin increased organ support–…

The old but new: Can unfractioned heparin and low molecular weight heparins inhibit proteolytic activation and cellular internalization of SARS-CoV2 by inhibition of …

FB Belen-Apak, F Sarialioglu - Medical hypotheses, 2020 - Elsevier
… the 2019 Novel Coronavirus (COVID-19) outbreak and … drug or vaccine for COVID-19. The
pathogenic infectivity of the … , unfractioned heparin and LMWH can be potential inhibitors of …