… of carcinogen-induced colon tumors in rodent models, even in some cases when administered
months after exposure to carcinogen … have also inhibited colon carcinogenesis in the Min …

… Involvement of prostaglandin E receptor subtype EP(4) in colon carcinogenesis. Cancer …
in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2). Cell 87: 803–809. …

… of COX-2 expression in carcinogenesis of … COX-2 expression was detected with tissue
microarray (TMA) and immunohistochemistry (IHC) procedure. The association between COX-2 …

… Sulindac, a known inhibitor of colon carcinogenesis, was included in the current study as a
… shown to be a strong inhibitor of colon carcinogenesis in animal assays and has reduced …

… on COX-2 expression, we transfected human colon carcinoma cells (Caco-2) with the human
COX-2 … overexpress COX-2 (human COX-2-sense, hCOX-2-s), express no COX-2 (human …

… risk of colon cancer and that the inhibition of colon carcinogenesis is mediated … cyclooxygenase
(COX) isozymes (COX-1 and -2). Overexpression of COX-2 has been observed in colon …

… whether a cyclooxygenase (COX)-2 inhibitor nimesulide … colon carcinogenesis using our
model to evaluate the efficacy of these drugs in prevention of IBD-related colon carcinogenesis. …

… however, the CRTH2 receptor viz the PGD2 receptor(11)]. Receptor knockout mice have
beenused to demonstrate a role for PGE2 in colon carcinogenesis in theMin mouse model (EP1 …

… To provide an understanding of the mechanism(s) of dietary fat-induced modulation of
colon tumor development, we have analyzed the expression of cyclooxygenase (COX), an …

… To determine whether elevated PKCβII levels contribute to colon carcinogenesis, we … colonic
epithelium to levels comparable with those observed in carcinogen-induced colon tumors ( …