Targeting NOX, INOS and COX2 in inflammatory cells: chemoprevention using food phytochemicals

A Murakami, H Ohigashi - International journal of cancer, 2007 - Wiley Online Library
… or induction of NOX, iNOS and COX-2, as well as some food … E 2 production through the
suppression of iNOS and COX-2 synthesis… ,7 has been shown to be involved in NOX activation.7 …

Involvement of p38 mitogen‐activated protein kinase in lipopolysaccharide‐induced iNOS and COX2 expression in J774 macrophages

CHEN, CHEN, LIN - Immunology, 1999 - Wiley Online Library
iNOS and COX-2 induction by AP-1 has been shown previously to be indispensable for
induction of iNOS and COX-2 … attenuated the induction of the iNOS and COX-2 proteins, stimuli,…

Cox-2, iNOS and p53 as play-makers of tumor angiogenesis

V Chiarugi, L Magnelli, O Gallo - … journal of molecular …, 1998 - spandidos-publications.com
… , Cox-1 and the inducible counterpart Cox-2; also NOS has a constitutive counterparts (cNOS)
and an inducible form, called iNOS. … The experiment involved the use of a selective Cox-2

Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF …

YJ Surh, KS Chun, HH Cha, SS Han, YS Keum… - Mutation Research …, 2001 - Elsevier
… up-regulation of COX-2 and/or iNOS has … involved in regulation of COX-2 and iNOS
expression. Several chemopreventive phytochemicals have been shown to inhibit COX-2 and iNOS

Ethanol-induced iNOS and COX-2 expression in cultured astrocytes via NF-κB

AM Blanco, M Pascual, SL Valles, C Guerri - Neuroreport, 2004 - journals.lww.com
… of iNOS and COX-2. Indeed, it has been recently suggested that NF-κB can function upstream
of COX-2 and iNOS … support the involvement of NF-κB in the induction of iNOS and COX-2, …

iNOS/COX-2 pathway interaction: a good molecular target for cancer treatment

F Cianchi, F Perna, E Masini - Current Enzyme Inhibition, 2005 - ingentaconnect.com
… A large body of evidence supports the hypothesis that products of iNOS and COX-2
pathways are involved in the regulation of several processes responsible for tumor growth. Both …

iNOS signaling interacts with COX-2 pathway in colonic fibroblasts

Y Zhu, M Zhu, P Lance - Experimental cell research, 2012 - Elsevier
… of COX-2 and iNOS gene expression, and explored possible mechanisms of interaction
between COX-2 and iNOS … C, not Ca 2+ , was involved in LPS-induced activation of COX-2 and …

Anti-nociceptive and anti-inflammatory effect of imperatorin: evidences for involvement of COX-2, iNOS, NFκB and inflammatory cytokines

G Singh, J Kaur, M Kaur, P Singh… - International Journal of …, 2020 - Taylor & Francis
… to confirm the involvement of nitric oxide pathway. Expression of COX-2 and iNOS was
quantified by immunofluorescence staining using antibodies for COX-2 and iNOS. The schematic …

Upregulation of iNOS by COX-2 in muscularis resident macrophage of rat intestine stimulated with LPS

M Hori, M Kita, S Torihashi… - American Journal …, 2001 - journals.physiology.org
… to clarify the cross-talk between iNOS and COX-2 in the muscularis resident … iNOS gene
expression might be mediated by autocrine regulation of PGs through the induction of COX-2

Distinct patterns of intracerebral hemorrhage‐induced alterations in NF‐κB subunit, iNOS, and COX2 expression

X Zhao, Y Zhang, R Strong, J Zhang… - Journal of …, 2007 - Wiley Online Library
… As COX-2 transcription may require involvement of transcription factors other than NF-κB,
it is possible that the stimulus generated in response to ICH is not sufficient to recruit all the …