… in bacterial genome editing and identifies fundamental genetic and phenotypic outcomes
of CRISPR targeting in bacteria, in the context of tool development, genome homeostasis, and …

… we show that CRISPR-Cas systems can be used for targeted genome editing in … genome
engineering using the CRISPR-Cas system works not only in highly recombinogenic bacteria …

… that the targeting of chromosomal genes by CRISPR/Cas systems is toxic and show …
bacterial genome. This suggests that CRISPR/Cas systems have played a greater role in bacterial …

… Sequencing of bacterial genome sequences is now a standard procedure, and the … tens of
thousands of bacterial genomes has had a major impact on our views of the bacterial world. In …

… show that CRISPR-Cas systems can be used for targeted genome editing in bacteria by the
… that at the same time eliminates CRISPR interference and introduces the desired mutations. …

… occurrence of CRISPR loci in the genomes of lactic acid bacteria (… draft genomes across 11
genera were studied and 66 CRISPR … We provide a comparative analysis of the CRISPR/cas …

… coli genome. This technology provides a framework for methods to manipulate bacterial
genomes using CRISPR… synergistically with preexisting bacterial genome engineering methods. …

… been as widely favored for bacterial genome editing. In this … with CRISPR-Cas-mediated
genome editing in bacteria and … , including CRISPR nickases, Cas12a, base editors, CRISPR-…

… for bacterial genomes reducing and possesses the potential for accelerating the genome …
prokaryotic NHEJ pathway safeguards the bacterial genomes against unexpected DSBs and …

… the genome engineering process, which is likely difficult to avoid but has never been reported
by other researchers for the bacterial genome … successfully employed CRISPR-Cas9 as an …