[HTML][HTML] Diversity of CRISPR-Cas immune systems and molecular machines
R Barrangou - Genome biology, 2015 - Springer
… various molecular machines to expand the molecular biology … , the diversity of CRISPR-Cas
systems will predictably further … , and valuable Cas molecular machines might be unearthed …
systems will predictably further … , and valuable Cas molecular machines might be unearthed …
DNA origami‐based single‐molecule CRISPR machines for spatially resolved searching
… In addition, previous studies have shown that CRISPR … of CRISPR/Cas 18 and single-molecule
analysis. In this study, we develop DNA origami-based CRISPR molecular machines with …
analysis. In this study, we develop DNA origami-based CRISPR molecular machines with …
A decade of discovery: CRISPR functions and applications
R Barrangou, P Horvath - Nature microbiology, 2017 - nature.com
… of CRISPR–Cas as adaptive immune systems in bacteria. In just a decade, the characterization
of CRISPR–Cas … their environment, and CRISPR-based molecular machines have been …
of CRISPR–Cas … their environment, and CRISPR-based molecular machines have been …
CRISPR-Cas: adapting to change
… regularly interspaced short palindromic repeats and associated proteins (CRISPR-Cas).
This molecular machinery can recognize and remember foreign nucleic acids by capturing and …
This molecular machinery can recognize and remember foreign nucleic acids by capturing and …
Engineering molecular machines for the control of cellular functions for diagnostics and therapeutics
The utilization of live cells as therapeutic materials provides controllability and complexity
unmatched by small molecules and biologic agents. Recent advancements have shown that …
unmatched by small molecules and biologic agents. Recent advancements have shown that …
Molecular mechanisms of CRISPR-Cas immunity in bacteria
PM Nussenzweig, LA Marraffini - Annual review of genetics, 2020 - annualreviews.org
… the targeting machinery to … molecular mechanisms used by different CRISPR-Cas systems
to execute these three phases of immunity. Figure 1 The different phases of the CRISPR-Cas …
to execute these three phases of immunity. Figure 1 The different phases of the CRISPR-Cas …
Molecular mechanisms of CRISPR–Cas spacer acquisition
J McGinn, LA Marraffini - Nature Reviews Microbiology, 2019 - nature.com
… CRISPR–Cas immune response. In this Progress article, we review recent studies that have
advanced our understanding of the molecular … two phases of CRISPR immunity that ensures …
advanced our understanding of the molecular … two phases of CRISPR immunity that ensures …
The next generation of CRISPR–Cas technologies and applications
A Pickar-Oliver, CA Gersbach - Nature reviews Molecular cell biology, 2019 - nature.com
… In this Review, we discuss recent advances in CRISPR–Cas tools for gene editing and
epigenetic modulation, before describing a diverse range of new CRISPR–Cas functions. We …
epigenetic modulation, before describing a diverse range of new CRISPR–Cas functions. We …
Development of CRISPR-Cas systems for genome editing and beyond
F Zhang - Quarterly Reviews of Biophysics, 2019 - cambridge.org
… CRISPR-Cas9 for genome editing within the broader context of the field and discuss our
work to discover novel Cas effectors and develop them into additional molecular … CRISPR-Cas …
work to discover novel Cas effectors and develop them into additional molecular … CRISPR-Cas …
Recent advances in molecular machines based on toehold‐mediated strand displacement reaction
… Thereafter, we review the recent progresses in DNA complex circuit, the assembly of AuNPs
driven by DNA molecular machines, and the detection of single nucleotide polymorphism (…
driven by DNA molecular machines, and the detection of single nucleotide polymorphism (…