Recent trends in CRISPR-Cas system: genome, epigenome, and transcriptome editing and CRISPR delivery systems
T Bae, JW Hur, D Kim, JK Hur - Genes & genomics, 2019 - Springer
… of CRISPR technology enabled genome editing to single base precision. Then, we discuss
the CRISPR based … regulation, epigenome editing, and RNA editing. Finally, we review the …
the CRISPR based … regulation, epigenome editing, and RNA editing. Finally, we review the …
CRISPR technologies for genome, epigenome and transcriptome editing
… Our ability to edit genomes lags behind our capacity to sequence them, but the growing
understanding of CRISPR biology and its application to genome, epigenome and transcriptome …
understanding of CRISPR biology and its application to genome, epigenome and transcriptome …
Mini review: genome and transcriptome editing using CRISPR-cas systems for haematological malignancy gene therapy
EK Elliott, LM Haupt, LR Griffiths - Transgenic Research, 2021 - Springer
… of existing CRISPR-Cas systems, along with new Cas effectors for transcriptome or RNA …
We also address the current diagnostic and therapeutic potential of CRISPR-Cas systems …
We also address the current diagnostic and therapeutic potential of CRISPR-Cas systems …
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors
… in editing efficiency. Finally, we show that an adenine base editor 7 can also induce
transcriptome-wide RNA edits… These results have implications for the use of base editors in both …
transcriptome-wide RNA edits… These results have implications for the use of base editors in both …
Genome and transcriptome engineering by compact and versatile CRISPR-Cas systems
G Aquino-Jarquin - Drug Discovery Today, 2023 - Elsevier
… the clinical utility of genome editing. Because CRISPR-Cas genome editing tools are prone
to errors, the newly developed CRISPR effectors require extensive characterization to be …
to errors, the newly developed CRISPR effectors require extensive characterization to be …
CRISPR–Cas13 precision transcriptome engineering in cancer
JT Granados-Riveron, G Aquino-Jarquin - Cancer research, 2018 - AACR
… Accordingly, RNA editing has been associated with tumorigenesis, by either … editing of
tumor-promoting genes or by transcriptome scale changes (34). Thus, precise nucleic acid editing …
tumor-promoting genes or by transcriptome scale changes (34). Thus, precise nucleic acid editing …
Comparative transcriptome and metabolome analyses of wild and mutant Oujiang color common carp through editing SCARB1 gene by CRISPR/Cas technology
… In this study, skin transcriptome and blood metabolites were conducted in the fishes of
wild-type whole red, mutant-type whole red, and mutant-type whole white colorations to identify …
wild-type whole red, mutant-type whole red, and mutant-type whole white colorations to identify …
[HTML][HTML] Transcriptome engineering with RNA-targeting type VI-D CRISPR effectors
… Our results present CasRx as a programmable RNA-binding module for efficient targeting
of cellular RNA, enabling a general platform for transcriptome engineering and future …
of cellular RNA, enabling a general platform for transcriptome engineering and future …
[HTML][HTML] Cas13d: a new molecular scissor for transcriptome engineering
… the Type VI CRISPR Cas system which has brought a new role to CRISPR to edit and target
… a gold standard in transcriptome editing and application beyond RNA editing with salutary …
… a gold standard in transcriptome editing and application beyond RNA editing with salutary …
Base editing: precision chemistry on the genome and transcriptome of living cells
… RNA-guided programmable nucleases from CRISPR systems generate precise breaks in …
Base editing is a newer genome-editing approach that uses components from CRISPR …
Base editing is a newer genome-editing approach that uses components from CRISPR …
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