Ubiquitin–proteasome-dependent degradation of a mitofusin, a critical regulator of mitochondrial fusion

MMJ Cohen, GP Leboucher… - Molecular biology of …, 2008 - Am Soc Cell Biol
… ubiquitin ligase targets a critical regulatory molecule at the mitochondrial outer membrane. …
of Mdm30p-mediated Fzo1p degradation in the multistep process of mitochondrial fusion. …

Reciprocal regulation of mitochondrial fission and fusion

R Sabouny, TE Shutt - Trends in biochemical sciences, 2020 - cell.com
… and mechanisms regulating dynamic changes in the mitochondrial network … regulation
of mitochondrial fusion and fission as an emerging trend in the regulation of mitochondrial

Mitochondrial fission‐fusion as an emerging key regulator of cell proliferation and differentiation

K Mitra - Bioessays, 2013 - Wiley Online Library
mitochondrial fusion can regulate cyclin E we need to study the mechanistic detail … regulation
of mitochondrial respiration by the fission-fusion molecules. Although mitochondrial fusion

Regulation of mitochondrial fusion and division

KL Cerveny, Y Tamura, Z Zhang, RE Jensen… - Trends in cell …, 2007 - cell.com
… that lead to mitochondrial fusion. In addition, recent in vitro membrane-fusion studies
suggest that the yeast mitofusin, Fzo1p, forms complexes that act in trans to fuse mitochondria [ …

Mitochondrial fusion and division: Regulation and role in cell viability

G Benard, M Karbowski - Seminars in cell & developmental biology, 2009 - Elsevier
… of mitochondrial research. The focus of this review is on the regulation of mitochondrial fusion
… /OPA1-dependent mitochondrial fusion, and Drp1-dependent mitochondrial division are …

Regulation and physiologic functions of GTPases in mitochondrial fusion and fission in mammals

N Ishihara, H Otera, T Oka, K Mihara - Antioxidants & redox …, 2013 - liebertpub.com
… weight GTPases regulating mitochondrial fusion and fission. … mitochondrial fusion (shown
in blue). OPA1 in the inner membrane/intermembrane space plays essential roles in the fusion

Regulating mitochondrial outer membrane proteins by ubiquitination and proteasomal degradation

M Karbowski, RJ Youle - Current opinion in cell biology, 2011 - Elsevier
… network (through fission and inhibition of fusion), and thus … a critical role of mitochondrial
membrane dynamics, impairments of mitochondrial fusion and/or fission lead to mitochondrial

[PDF][PDF] Two deubiquitylases act on mitofusin and regulate mitochondrial fusion along independent pathways

F Anton, G Dittmar, T Langer, M Escobar-Henriques - Molecular cell, 2013 - cell.com
mitochondrial fusionregulatory role of ubiquitylation during mitochondrial fusion. Our
findings uncover two ubiquitylation pathways, which either promote or inhibit mitochondrial fusion. …

[HTML][HTML] New insights into mitochondrial fusion

Y Zhang, DC Chan - FEBS letters, 2007 - Elsevier
Regulation of mitofusin activity Because mitofusins are critical for maintenance of mitochondrial
fusion… In yeast, stringent regulation of Fzo1p turnover is important for maintaining normal …

[HTML][HTML] Mitochondrial fusion and ERK activity regulate steroidogenic acute regulatory protein localization in mitochondria

A Duarte, AF Castillo, EJ Podestá, C Poderoso - PloS one, 2014 - journals.plos.org
mitochondrial StAR protein. Together our results unveil the requirement of mitochondrial fusion
in the regulation of the … We here establish the relevance of mitochondrial phosphorylation …