… The purpose of this critical review of induced hyperthermia testing is: (1) To describe the long
… (2) To raise unanswered questions concerning mechanisms of HR, particularly the existing …

… paper we review our current understanding of the cellular and molecular mechanisms of …
We also critically review the use of glucocorticosteroid therapy to: (1) improve recovery from …

… animals that is used to model multiple sclerosis (MS). However, few … differences in pathological
disease mechanisms, importantly it … The use of EAE is critically appraised with the aim of …

… acetate have been available for the treatment of multiple sclerosis (MS) for over a decade …
differ from established immunotherapies with regard to their mechanisms of action, modes of …

… of numerous effective drugs with diverse mechanisms of actions, routes of administration …
a thorough analysis of the benefit/risk ratio is required. This article reviews the mechanisms of …

… of the blood-brain barrier resulting from diverse mechanisms including trauma or a second,
… forming mechanism which is operative only in the central nervous system. Multiple sclerosis …

… This review summarizes in a critical way, the diagnostic criteria (historical and updated) and
the definitions/characteristics of MS of the various variants/subtypes of CNS demyelinating …

… Despite the foregoing negative evidence, however, there is a basis for considering allergy
as a mechanism for the induction of multiple sclerosis. The available data come from the …

… The most common epigenetic mechanisms are … multiple sclerosis (SPMS) patients, the
cortisol response to the neuropeptide was lower than in primary progressive multiple sclerosis (…

… Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous …
In this section, we will present frequently used MS models and critically address their place …