Protective effect of ellagic acid, a natural polyphenolic compound, in a murine model of Crohn's disease

MA Rosillo, M Sanchez-Hidalgo, A Cárdeno… - Biochemical …, 2011 - Elsevier
… , ellagic acid, present in some fruits such as pomegranate, raspberries and nuts among others,
in an experimental murine model of Crohn's disease … model of Crohn's disease, alleviates …

Dietary supplementation of an ellagic acid-enriched pomegranate extract attenuates chronic colonic inflammation in rats

MA Rosillo, M Sánchez-Hidalgo, A Cárdeno… - Pharmacological …, 2012 - Elsevier
… supplementation of EA contributes in the beneficial effect of PE in this experimental colitis
model and may be a novel therapeutic strategy to manage inflammatory bowel disease (IBD). …

Intestinal anti-inflammatory activity of ellagic acid in the acute and chronic dextrane sulfate sodium models of mice colitis

M Marín, RM Giner, JL Ríos, MC Recio - Journal of ethnopharmacology, 2013 - Elsevier
Inflammatory bowel disease (IBD) is a chronic, relapsing, inflammatory disorder of the
gastrointestinal tract that encompasses two pathologies, namely Crohn's disease (CD) and …

NF-κB-dependent anti-inflammatory activity of urolithins, gut microbiota ellagic acid-derived metabolites, in human colonic fibroblasts

A González-Sarrías, M Larrosa… - British Journal of …, 2010 - cambridge.org
… of inflammatory bowel diseases such as ulcerative colitis and Crohn’s disease has risen in
… The increasing incidence of inflammatory bowel disease has been associated with changes …

Antibacterial potential of ellagic acid and gallic acid against IBD bacterial isolates and cytotoxicity against colorectal cancer

D Cota, D Patil - Natural Product Research, 2023 - Taylor & Francis
… This study aims at evaluating antibacterial activity of Ellagic acid and gallic acid against
isolated four E.coli strains from inflammatory bowel disease patients and estimate cytotoxicity of …

Ellagic Acid Prevented Dextran-Sodium-Sulfate-Induced Colitis, Liver, and Brain Injury through Gut Microbiome Changes

D Kim, JS Kim, JH Kwon, IS Kwun, MC Baek, GS Kwon… - Antioxidants, 2023 - mdpi.com
Inflammatory bowel disease (IBD) affects millions of people … Recent in vivo and in vitro studies
reported that ellagic acid (… of EA on the DSS-induced IBD mouse model was mediated by …

The role of dietary polyphenols in the management of inflammatory bowel disease

MH Farzaei, R Rahimi… - Current Pharmaceutical …, 2015 - ingentaconnect.com
… of ellagic acid-enriched pomegranate extract in animal models of colitis is similar to
sulphasalazine [77]. Ellagic acid or benzoaric acidEllagic acid demonstrated protective effect on …

Ellagic acid protects Caco-2 cell monolayers against inflammation-induced permeabilization

DE Iglesias, E Cremonini, CG Fraga… - Free Radical Biology and …, 2020 - Elsevier
… Increased permeability is observed in chronic inflammatory conditions, including
inflammatory bowel diseases, celiac diseases and obesity- and diabetes-associated chronic …

Gut microbiota conversion of dietary ellagic acid into bioactive phytoceutical urolithin A inhibits heme peroxidases

P Saha, BS Yeoh, R Singh, B Chandrasekar… - PloS one, 2016 - journals.plos.org
… However, they also contribute to tissue damage and perpetuation of inflammatory disorders
including inflammatory bowel disease (IBD) [46–49]. Accordingly, there is significant interest …

The alleviating effect of ellagic acid on DSS-induced colitis via regulating gut microbiomes and gene expression of colonic epithelial cells

X Li, L Xu, X Peng, H Zhang, M Kang, Y Jiang, H Shi… - Food & Function, 2023 - pubs.rsc.org
Inflammatory bowel disease (IBD) is a periodic chronic intestinal inflammation that directly
causes gastrointestinal impairment and results in weight loss, abdominal pain, persistent …