… Fibroblast growth factors (FGFs) are crucial signalling molecules involved in normal cell …
of individual FGFs on tumour initiation and progression. Tumour development is commonly …

… The metastatic niche plays an important role within the crucial factors that determine the
success or failure of metastasis. A series of events take place in its formation, including: the …

… an important role in tumor initiation and progression. Fusion between somatic cells that
have undergone a set of specific mutations and normal stem cells might explain the extensive …

… from the insulin resistance syndrome is emerging as another important risk factor for cirrhosis
and HCC 5 . The major risk factors for the development of HCC are summarized in Table 1. …

… This review highlights the roles of CSCs in tumour initiation, progression and metastasis …
stages of cancer progression. We delineate the cross-talks between CSCs with the tumour …

… an important barrier against tumour initiation and progression. Akin to the earlier landmark
discoveries that lead to the identification of the major cancer-… properties of tumour suppressors …

… for human cancer. In this review, the diverse functions of EMT-TFs in cancer progression,
the … These findings may imply the crucial role of EMT-TFs in tumor initiation as activators of …

… microenvironment, the growth and proliferation of cancer cells in the primary … progression
of cancer either by local expansion and/or metastasis, it is important to understand the cancer …

… in protecting transformed cells from macrophage-induced apoptosis during tumor initiation
… a crucial role in tumor initiation, NF-κB has also been found to play a role in allowing cancer …

… 11,29,30,31 inhibition of individual MRs or MR pairs — induces crucial loss of tumour state
and abrogation of tumour viability or rescue of drug sensitivity, in vitro and in vivo. This has …