Conformational changes studied by cryo-electron microscopy
HR Saibil - nature structural biology, 2000 - nature.com
… structure of the ribosome has been defined by cryo-EM, which has provided starting phases
for crystal structure … states in the translocation cycle are being defined by cryo-EM studies. …
for crystal structure … states in the translocation cycle are being defined by cryo-EM studies. …
Symmetry‐free cryo‐EM structures of the chaperonin TRiC along its ATPase‐driven conformational cycle
… We present five cryo-EM structures of TRiC in apo and nucleotide-induced states … structures
reveal the intra- and inter-ring subunit interaction pattern changes during the ATPase cycle. …
reveal the intra- and inter-ring subunit interaction pattern changes during the ATPase cycle. …
An ensemble of cryo-EM structures of TRiC reveal its conformational landscape and subunit specificity
… conformational cycle and is essential in maintaining protein homeostasis. Here, we determined
an ensemble of cryo-electron microscopy (cryo-EM) structures … in the ATPase-cycle in our …
an ensemble of cryo-electron microscopy (cryo-EM) structures … in the ATPase-cycle in our …
The translation elongation cycle—capturing multiple states by cryo-electron microscopy
J Frank - Philosophical Transactions of the Royal Society …, 2017 - royalsocietypublishing.org
… rounds of the peptide elongation cycle, one for each amino … steps in the immediately following
cycles of elongation, until it exits … structures closely related to one another in conformation. …
cycles of elongation, until it exits … structures closely related to one another in conformation. …
Cryo-EM analysis of the conformational landscape of human P-glycoprotein (ABCB1) during its catalytic cycle
… cycle. Since P-gp exhibits basal ATPase activity, we evaluated hP-gp conformations at four
different points in the ATPase cycle … Despite the low resolution of the cryo-EM density maps, …
different points in the ATPase cycle … Despite the low resolution of the cryo-EM density maps, …
Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution
J Ecken, SM Heissler, S Pathan-Chhatbar, DJ Manstein… - Nature, 2016 - nature.com
… important structural insights into the myosin motor cycle when … conformational changes in
F-actin, we compared the ATM structure with our reprocessed F-actin–tropomyosin structure. …
F-actin, we compared the ATM structure with our reprocessed F-actin–tropomyosin structure. …
Cryo-EM structures capture the transport cycle of the P4-ATPase flippase
M Hiraizumi, K Yamashita, T Nishizawa, O Nureki - Science, 2019 - science.org
… of ATP8A1 drive a cycle of conformations in which lipids bind … Here, we report the cryo–electron
microscopy structures of … , elucidating the lipid translocation cycle of this P4-ATPase. ATP-…
microscopy structures of … , elucidating the lipid translocation cycle of this P4-ATPase. ATP-…
Cryo-EM structures of the archaeal PAN-proteasome reveal an around-the-ring ATPase cycle
P Majumder, T Rudack, F Beck… - Proceedings of the …, 2019 - National Acad Sciences
… Interestingly, the plane of the OB ring adjusts with the conformation of the … structures to be
snapshots in the proteasomal catalytic cycle, we presume there exist additional conformational …
snapshots in the proteasomal catalytic cycle, we presume there exist additional conformational …
X‐ray and Cryo‐EM structures reveal mutual conformational changes of Kinesin and GTP‐state microtubules upon binding
… crystal structure of nucleotide‐free KIF5C and the cryo‐EM structure … These structures showed
the first detailed structural … rigor conformation, which enables the effective ATP cycling with …
the first detailed structural … rigor conformation, which enables the effective ATP cycling with …
[HTML][HTML] Novel cryo-EM structure of an ADP-bound GroEL–GroES complex
SS Kudryavtseva, EB Pichkur, IA Yaroshevich… - Scientific reports, 2021 - nature.com
… cryo-EM structures of GroEL–GroES have moderate resolutions ranging from 7.7 to 15.9 Å
27,44 . In this work, with the use of cryo-EM, we resolved two conformations … of the cycle, and …
27,44 . In this work, with the use of cryo-EM, we resolved two conformations … of the cycle, and …
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