Blood neutrophil counts in HIV-infected patients with cryptococcal meningitis: Association with mortality

AK Musubire, DB Meya, J Rhein, G Meintjes… - PLoS …, 2018 - journals.plos.org
blood neutrophil counts at the baseline in HIV-infected patients with cryptococcal meningitis
is … This association between higher blood neutrophil count and mortality is maintained even …

The change in the neutrophil/lymphocyte ratio predicts the prognosis of patients with cryptococcal meningitis

K Zhang, H Li, L Zhang, W Liao, L Cai, X Li, W Pan… - Mycopathologia, 2021 - Springer
… The clinical data included white blood cells, platelets, lymphocytes, neutrophils, the PLR
and NLR at admission and after 2 weeks and 4 weeks in the hospital. We divided patients into …

Fungal CNS infections in Africa: the neuroimmunology of cryptococcal meningitis

SH Mohamed, TK Nyazika, K Ssebambulidde… - Frontiers in …, 2022 - frontiersin.org
… neoformans infection were monocytes and neutrophils recruited from the blood, and that
infection and inflammation were largely confined to the perivascular spaces where CNS-…

Real-time in vivo imaging reveals the ability of neutrophils to remove Cryptococcus neoformans directly from the brain vasculature

M Zhang, D Sun, G Liu, H Wu, H Zhou… - Journal of Leucocyte …, 2016 - academic.oup.com
neutrophils are typically the first immune cells attracted to an infection site, little is known
about how neutrophils … that neutrophils migrate to the arrested Cryptococcus neoformans, a …

… value of cerebrospinal fluid Neutrophil Gelatinase-Associated Lipocalin for differentiation of bacterial meningitis from tuberculous meningitis or cryptococcal meningitis …

Q Wang, Q Lin, H Wang, M Tang, K Fan… - Journal of Translational …, 2023 - Springer
diagnosis between bacterial meningitis (BM) and tuberculous meningitis (TBM) or cryptococcal
meningitisNeutrophil Gelatinase-Associated Lipocalin (NGAL) has been reported as a …

Cryptococcal meningitis

L Tugume, K Ssebambulidde, J Kasibante… - Nature Reviews …, 2023 - nature.com
… of altered mental state and high fungal burden at diagnosis 39 . Moreover, the rate of … Early
during the disease course, neutrophilic pleocytosis may be found in the CSF. Neutrophils are …

… -associated immune signature, characterized by monocyte deactivation and an increased interleukin 10 level, is a predictor of death in cryptococcal meningitis

JE Scriven, LM Graham, C Schutz… - The Journal of …, 2016 - academic.oup.com
… Variables measured included the relative frequency of circulating neutrophils, … blood cells
[WBCs]); the proportion of CD16 − neutrophils (recorded as the percentage of total neutrophils)…

Innate immune evasion strategies against Cryptococcal meningitis caused by Cryptococcus neoformans

CL Yang, J Wang, LL Zou - Experimental and …, 2017 - spandidos-publications.com
… neoformans may target the brain instead of the lungs and cross the blood‑brain barrier (BBB) …
that neutrophils use to defend against fungal infection (22). In addition, neutrophils contain …

Two patients with cryptococcal meningitis and idiopathic CD4 lymphopenia: defective cytokine production and reversal by recombinant interferon-γ therapy

MG Netea, AE Brouwer… - Clinical infectious …, 2004 - academic.oup.com
… presented with severe cryptococcal meningitis. Laboratory … of anti-cryptococcal activity of
neutrophils and macrophages [8]… The diagnosis of cryptococcal meningitis was made on the …

Differences in immunologic factors among patients presenting with altered mental status during cryptococcal meningitis

S Lofgren, KH Hullsiek, BM Morawski… - The Journal of …, 2017 - academic.oup.com
cryptococcal meningitis [3, 5]. In each trial, we defined altered mental status as a Glasgow
Coma Scale (GCS) score of <15 at the time of diagnosis of cryptococcal meningitisneutrophils