High-dose amphotericin B with flucytosine for the treatment of cryptococcal meningitis in HIV-infected patients: a randomized trial

T Bicanic, R Wood, G Meintjes, K Rebe… - Clinical infectious …, 2008 - academic.oup.com
… The 2-week regimen of AmB plus flucytosine was well tolerated in this study, as it was in the
… for many fungal infections and has been administered with flucytosine for treatment of CM …

Fluconazole alone or combined with flucytosine for the treatment of AIDS-associated cryptococcal meningitis

E Milefchik, M Ann Leal, R Haubrich… - Medical …, 2008 - academic.oup.com
… An all oral treatment for cryptococcal meningitis is attractive, particularly where amphotericin
… and flucytosine are available in oral formulations and have activity against Cryptococcus

A comparison of amphotericin B alone and combined with flucytosine in the treatment of cryptoccal meningitis

JE Bennett, WE Dismukes, RJ Duma… - … England Journal of …, 1979 - Mass Medical Soc
cryptococcal meningitis with a newer regimen containing both amphotericin B and flucytosine.
… Adverse reactions to flucytosine occurred in 11 of 34 patients but were not life threatening. …

Outcomes of flucytosine-containing combination treatment for cryptococcal meningitis in a South African national access programme: a cross-sectional observational …

RC Mashau, ST Meiring, VC Quan, J Nel… - The Lancet Infectious …, 2022 - thelancet.com
… inpatients with cryptococcal meningitis treated with flucytosine in … We found that flucytosine
combination treatment could be … cryptococcal meningitis are currently treated with flucytosine, …

Fluconazole combined with flucytosine for treatment of cryptococcal meningitis in patients with AIDS

RA Larsen, SA Bozzette, BE Jones… - Clinical Infectious …, 1994 - academic.oup.com
… arise when flucytosine is combined with fluconazole [9], we conducted a clinical trial in
which we combined fluconazole and flucytosine for the treatment of cryptococcal meningitis in …

Treatment of cryptococcal meningitis with combination amphotericin B and flucytosine for four as compared with six weeks

WE Dismukes, G Cloud, HA Gallis… - … England Journal of …, 1987 - Mass Medical Soc
… Five other cases of cryptococcal meningitis were reported among 182 … cryptococcal
meningitis be given at least six weeks of combination therapy with amphotericin B and flucytosine

Antifungal combinations for treatment of cryptococcal meningitis in Africa

SF Molloy, C Kanyama, RS Heyderman… - … England Journal of …, 2018 - Mass Medical Soc
… with cryptococcal meningitis to receive an oral regimen (fluconazole [1200 mg per day] plus
flucytosine [… In conclusion, in our trial, 1 week of amphotericin B plus flucytosine was the most …

Treatment of cryptococcal meningitis associated with the acquired immunodeficiency syndrome

CM Van der Horst, MS Saag, GA Cloud… - … England Journal of …, 1997 - Mass Medical Soc
… This study was designed to address a number of critical questions in the management of
AIDS-associated cryptococcal meningitis: Does the addition of flucytosine offer any advantage …

Combination flucytosine and high-dose fluconazole compared with fluconazole monotherapy for the treatment of cryptococcal meningitis: a randomized trial in Malawi

JC Nussbaum, A Jackson, D Namarika… - Clinical infectious …, 2010 - academic.oup.com
flucytosine to unequivocally demonstrate the microbiological efficacy of combining flucytosine
… and rarely limited treatment in this study, suggesting that flucytosine could be used with …

Cryptococcal meningitis treatment strategies affected by the explosive cost of flucytosine in the United States: a cost-effectiveness analysis

M Merry, DR Boulware - Clinical Infectious Diseases, 2016 - academic.oup.com
… This analysis suggests that amphotericin plus flucytosine is a highly desirable upgrade
over amphotericin plus fluconazole for the treatment of cryptococcal meningitis. Amphotericin …