… neoformans capsule regulation occur at the level of transcription. For example, incubation in
the presence … signaling pathways likely regulate the complex biology of the capsule. The C. …

… in capsule regulation have been identified, most of the mechanisms involved in modulating
capsule size … Certain elements of other transduction pathways do appear to regulate capsule …

… of capsule regulation we performed RNA-Seq on strains lacking either Ada2 or one of two
other capsule … These studies supported the role of Ada2 in the direct regulation of capsule and …

… Capsule size is also regulated by the cell cycle [Citation50] and is larger in cells grown in …
What are the mechanisms that regulate capsule size? At some point the capsule stops growing …

… Synthesis of a polysaccharide capsule is a critical determinant of virulence for Cryptococcus
neoformans. Isolates from human cerebrospinal fluid (CSF)' have large capsules which are …

… highly regulated nature of this virulence factor. Efforts to understand capsule regulation have
… In the search for the molecular basis of capsule regulation, a cAMP-signaling pathway that …

… Based on the SAGE data, we hypothesized that PKA could influence capsule formation by
regulating secretion. We therefore examined the effects of known vesicle trafficking inhibitors …

… The ability of the pathogenic fungus Cryptococcus neoformans to cause life-threatening …
of a capsule consisting of polysaccharide fibers. The size of the cell-associated capsule is …

… capsule's release into the medium is an active phenomenon regulated by the cell, or if it is
just an unspecific capsule shedding… It is noteworthy that practically all our information about C. …

… neoformans contains primarily the … of capsular material and its specifi c polysaccharide
components on the innate and T cell immune response and examines the regulatory mechanisms …