Cell identity and sexual development in Cryptococcus neoformans are controlled by the mating-type-specific homeodomain protein Sxi1α

CM Hull, RC Davidson, J Heitman - Genes & development, 2002 - genesdev.cshlp.org
… SXI1α establishes α cell identity and controls … cells is sufficient to drive a/α sexual development.
SXI1α is the first example of a key regulator of cell identity and sexual differentiation in C. …

Cryptococcus neoformans: morphogenesis, infection, and evolution

X Lin - Infection, Genetics and Evolution, 2009 - Elsevier
neoformans strains have the ability to initiate hyphal growth during a–α mating, and that
putting the α cell identity gene SXI1α in a haploid a cell or vice versa can initiate self-…

Profiling a killer, the development of Cryptococcus neoformans

L Kozubowski, J Heitman - FEMS microbiology reviews, 2012 - academic.oup.com
… Similar to other fungi, the cell-type identity of Cryptococcus is specified by pheromone and
receptor genes and homeodomain transcription factor genes within the MAT locus that serve …

Genetics of Cryptococcus neoformans

CM Hull, J Heitman - Annual review of genetics, 2002 - annualreviews.org
… These congenic diploid strains can be transformed and used to studykey features of cell
identity and to establish that genes are essential(43,83). The filaments produced by …

Uniqueness of the mating system in Cryptococcus neoformans

CM McClelland, YC Chang, A Varma… - Trends in …, 2004 - cell.com
… Of these, the MATα-specific homeodomain protein Sxi1αp was identified as necessary
and sufficient to designate α cell identity in a manner analogous to the mammalian sex …

[图书][B] Cryptococcus neoformans

A Casadevall, JR Perfect - 1998 - Citeseer
C. neoformans cells were added to the macrophage suspension at a density of 5 105 cells/ml
of culture medium with 10 g/ml of monoclonal antibody 1887 as an opsonin. Macrophage-…

Allelic Exchange of Pheromones and Their Receptors Reprograms Sexual Identity in Cryptococcus neoformans

BC Stanton, SS Giles, MW Staudt, EK Kruzel… - PLoS …, 2010 - journals.plos.org
… and pheromone receptors alone are sufficient to confer haploid cell identity in C. … control
of haploid cell identity in C. neoformans is mediated by MAT-encoded cell-cell communication …

Identification of Cryptococcus neoformans Temperature-Regulated Genes with a Genomic-DNA Microarray

PR Kraus, MJ Boily, SS Giles, JE Stajich, A Allen… - … cell, 2004 - Am Soc Microbiol
… in the human-pathogenic fungus Cryptococcus neoformans during growth at 37C. Genes
with … during growth at 37C, suggesting that a conserved transcriptional program is used by C. …

Life Cycle of Cryptococcus neoformans

Y Zhao, J Lin, Y Fan, X Lin - Annual review of microbiology, 2019 - annualreviews.org
Cryptococcus neoformans is a ubiquitous environmental fungus and an opportunistic …
cryptococcal meningitis. Advances in genomics, genetics, and cellular and molecular biology of C. …

Cryptococcus neoformans and Cryptococcus gattii, the etiologic agents of cryptococcosis

KJ Kwon-Chung, JA Fraser… - Cold Spring …, 2014 - perspectivesinmedicine.cshlp.org
Cryptococcus neoformans was first isolated from peach juice by Sanfelice in 1894 in Italy
and was named Saccharomyces neoformans (… about the identity of the cryptococcosis agent …