… is essential for the pathogenic mechanisms of Cryptococcus neoformans. On the basis of the
… cryptococcal virulence, we analyzed the role of this enzyme in polysaccharide release by C. …

… There is a significant need for developing compounds that kill Cryptococcus neoformans,
the fungal pathogen that causes meningoencephalitis in immunocompromised individuals. …

… , the opportunistic fungal pathogen Cryptococcus neoformans must survive and thrive upon
subjection to host temperature. Primary maintenance of cell integrity is controlled through the …

… Cryptococcus neoformans. Conversely, loss of the PKA regulatory subunit encoded by pkr1
results in overproduction of capsule and hypervirulence. We compared the transcriptomes …

… and Noc-treated cells were mostly budded, … of cell polarity and the subsequent growth of
the bud. While 47% of the control cells had the mCherry-Cse4 signal either in the daughter cell …

… /PKA pathway in the basidiomycete pathogen Cryptococcus neoformans. This fungus is the
… and subsequently found that extracts containing polar lipids were stimulatory. The ability of …

… In this study, we analyzed the role of lipid droplets during the interaction of Cryptococcus
neoformans with macrophages in the presence and the absence of exogenous lipids, in …

… Cryptococcus neoformans (Cn) is the most common cause of fungal meningitis worldwide.
In … Complex sphingolipids are formed with the addition of a polar group to ceramide (or …

… Our results suggest that both CchA and MidA are critical for conidial development, hyphal
polarity establishment, and cell wall components in low-calcium environmental conditions. …

… , we considered whether the release of polar lipids from amoeba membranes could be a
step in amoeba-mediated capsular enlargement and thus evaluated the requirement for fungal …