A systematic review of fluconazole resistance in clinical isolates of Cryptococcus species
… Cryptococcus neoformans was the most common species isolated in all the studies.
While 26 (89.7%) of the studies were conducted on isolates from incident episodes of …
While 26 (89.7%) of the studies were conducted on isolates from incident episodes of …
Dynamic and Heterogeneous Mutations to Fluconazole Resistance in Cryptococcus neoformans
J Xu, C Onyewu, HJ Yoell, RY Ali… - Antimicrobial Agents …, 2001 - Am Soc Microbiol
… Resistance to this antifungal agent has been reported. This study investigated the
patterns of mutation to fluconazole resistance inC. neoformans in vitro. The MIC of …
patterns of mutation to fluconazole resistance inC. neoformans in vitro. The MIC of …
… and characterization of a Cryptococcus neoformans ATP binding cassette (ABC) transporter‐encoding gene, CnAFR1, involved in the resistance to fluconazole
… is involved in fluconazole resistance of C. neoformans. Our findings therefore reveal that an
active drug efflux mechanism can be involved in the development of azole resistance in this …
active drug efflux mechanism can be involved in the development of azole resistance in this …
Heteroresistance to Fluconazole in Cryptococcus neoformans Is Intrinsic and Associated with Virulence
E Sionov, YC Chang, HM Garraffo… - Antimicrobial agents …, 2009 - Am Soc Microbiol
… reported in Cryptococcus neoformans strains isolated from an azole therapy failure case of
cryptococcosis in an … In 1999, we reported the occurrence of azole resistance in strains of C. …
cryptococcosis in an … In 1999, we reported the occurrence of azole resistance in strains of C. …
Cryptococcus neoformans Yap1 is required for normal fluconazole and oxidative stress resistance
… involved in fluconazole resistance in Cryptococcus is limited. Here we report the identification
of an important genetic determinant of fluconazole resistance in C. neoformans that …
of an important genetic determinant of fluconazole resistance in C. neoformans that …
Characterization of Heteroresistance to Fluconazole among Clinical Isolates of Cryptococcus neoformans
T Yamazumi, MA Pfaller, SA Messer… - Journal of clinical …, 2003 - Am Soc Microbiol
… neoformans exists in a significant proportion of clinical isolates and that fluconazole resistance
can … On the other hand, this study confirmed that fluconazole resistance can be developed …
can … On the other hand, this study confirmed that fluconazole resistance can be developed …
Heteroresistance to Fluconazole and Voriconazole inCryptococcus neoformans
P Mondon, R Petter, G Amalfitano… - Antimicrobial Agents …, 1999 - Am Soc Microbiol
… The effect of temperature on the expression of fluconazole resistance was more profound
for resistant clone B-4548 R derived from the isolate from patient B. Only 9% of the cells of B-…
for resistant clone B-4548 R derived from the isolate from patient B. Only 9% of the cells of B-…
Heteroresistance of Cryptococcus gattii to Fluconazole
A Varma, KJ Kwon-Chung - Antimicrobial Agents and …, 2010 - Am Soc Microbiol
… neoformans strains in mice and resistance to xenobiotics unrelated to … were more virulent
in mice and more resistant to xenobiotics that are unrelated to fluconazole, as reported for C. …
in mice and more resistant to xenobiotics that are unrelated to fluconazole, as reported for C. …
Increased antifungal drug resistance in clinical isolates of Cryptococcus neoformans in Uganda
… neoformans in the environment, the increasing use of triazole fungicides by farmers in
Uganda could be a factor in the increased fluconazole resistance observed in our studies. …
Uganda could be a factor in the increased fluconazole resistance observed in our studies. …
Fluconazole-Resistant Cryptococcus neoformans Isolated from an Immunocompetent Patient without Prior Exposure to Fluconazole
R Orni-Wasserlauf, E Izkhakov… - Clinical infectious …, 1999 - academic.oup.com
… previously treated with fluconazole [5–9]. Herein, we describe a case of meningitis due to
fluconazole-resistant C. neoformans in an immunocompetent patient without prior exposure to …
fluconazole-resistant C. neoformans in an immunocompetent patient without prior exposure to …
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