Hybrid genotypes in the pathogenic yeast Cryptococcus neoformans

T Boekhout, B Theelen, M Diaz, JW Fell… - …, 2001 - microbiologyresearch.org
… We propose a complex life cycle for the pathogen comprising both recombination and clonal
expansion, and we suggest a role for the sexual Filobasidiella state in this process in vivo. …

Transcription Factor Nrg1 Mediates Capsule Formation, Stress Response, and Pathogenesis in Cryptococcus neoformans

KL Cramer, QD Gerrald, CB Nichols, MS Price… - Eukaryotic …, 2006 - Am Soc Microbiol
… The human fungal pathogen Cryptococcus neoformans lives primarily in the external …
Without the expression of these phenotypes, C. neoformans is crippled for survival within …

Cryptococcosis

M Chayakulkeeree, JR Perfect - Diagnosis and treatment of human …, 2008 - Springer
… The life cycle of C. … of infection due to Cryptococcus neoformans in Australia and New
Zealand. Australasian … Persistence of Cryptococcus neoformans in seminal fluid and urine under …

Mixed Infections and In Vivo Evolution in the Human Fungal Pathogen Cryptococcus neoformans

M Desnos-Ollivier, S Patel, AR Spaulding, C Charlier… - MBio, 2010 - Am Soc Microbiol
Cryptococcus neoformans is a life-threatening human fungal pathogen responsible for an
estimated 1 million cases of cryptococcosis/year, … of clinical isolates and gain knowledge of C. …

[HTML][HTML] Regional pattern of the molecular types of Cryptococcus neoformans and Cryptococcus gattii in Brazil

L Trilles, MS Lazéra, B Wanke, RV Oliveira… - Memórias do Instituto …, 2008 - SciELO Brasil
… The molecular types of 443 Brazilian isolates of Cryptococcus neoformans and Cryptococcus
gattii were analyzed to determine their geographic distribution within Brazil and their …

Cryptococcus neoformans constitutes an ideal model organism to unravel the contribution of cellular aging to the virulence of chronic infections

T Bouklas, BC Fries - Current opinion in microbiology, 2013 - Elsevier
… their life cycle (reviewed in [38]). Even if many fungi have retained the ability to replicate
sexually [39], this appears to occur infrequently and only in the environment. The life cycle of …

The Production of Monokaryotic Hyphae by Cryptococcus neoformans Can Be Induced by High Temperature Arrest of the Cell Cycle and Is Independent of Same-Sex …

J Fu, IR Morris, BL Wickes - PLoS Pathogens, 2013 - journals.plos.org
Cryptococcus neoformans is a heterothallic fungal pathogen of humans and animals. … the
cell cycle and occurs in haploid cells in the absence of sexual reproduction. Cells grown at 37C

Ras1 and Ras2 contribute shared and unique roles in physiology and virulence of Cryptococcus neoformans

MS Waugh, CB Nichols, CM DeCesare… - …, 2002 - microbiologyresearch.org
… The Ras1 signal transduction pathway controls the ability of the pathogenic fungus
Cryptococcus neoformans to grow at high temperatures and to mate. A second RAS gene was …

Last but not yeast—The many forms of Cryptococcus neoformans

PR Stempinski, GR Gerbig, SD Greengo… - PLoS …, 2023 - journals.plos.org
Cryptococcus neoformans is an encapsulated human fungal pathogen and the etiological
agent of cryptococcosis and cryptococcal meningitis [2]. Cryptococcal infections begin with the …

Virulence-associated enzymes of Cryptococcus neoformans

F Almeida, JM Wolf, A Casadevall - Eukaryotic cell, 2015 - Am Soc Microbiol
… in the virulence-associated enzymes from Cryptococcus neoformans. The enzymatic suite of
C. … The facultative intracellular fungal pathogen Cryptococcus neoformans is the causative …