… of the fungal pathogen Cryptococcus neoformans is controlled by a bipolar mating system
… and a mating-type alleles from two divergent varieties were cloned and sequenced. The C. …

… Cryptococcus neoformans is a globally distributed human … haploid cells of α and a mating
types 2 , yet the vast majority of … of opposite mating type in organisms with two mating types (or …

… mating between haploid MATa and MATα cells. Here we describe the isolation of part of the
MATa mating-type … MATa mating type in genetic crosses, maps within the mating-type locus …

… neoformans and virulence were nonisogenic. It became clear that isogenic strains had to be
… cannot be achieved, because C. neoformans never switches mating type according to our …

… to be unique among the fungi with characterized mating type loci. This review will highlight
what is known with regard to the role that mating type plays in virulence in C. neoformans. …

… differences between the two mating types render MATα mating-type strains more fit for …
of MATα mating types both in nature and in clinical isolates. Cryptococcus neoformans is a …

… the mating-type (MAT) loci in many fungi, due to the highly diverged and rearranged nature
between alleles defining opposite sexes or mating-types. … fungus Cryptococcus neoformans, …

… Cryptococcus neoformans by Kwon-Chung (1, 2), it has been considereda bipolar heterothallic
basidiomycete with two mating types… between the two mating types occurs and generates …

… serotype A mating type α specific amplicons but negative for mating type a specific … mating
type information. This result is consistent with the predominance of the α mating type in the C…

… neoformans within the mating pheromones (10). Our studies further demonstrate that the
serotype, mating type, and ploidy of C. neoformans strains can be readily established by rapid …