Cryptococcus neoformans melanin and virulence: mechanism of action

Y Wang, P Aisen, A Casadevall - Infection and immunity, 1995 - Am Soc Microbiol
… Black melanin-like pigments are produced by several neurotropic fungi, including
Cryptococcus neoformans. Pigment production is associated with virulence. In media containing …

Melanin, melanin" ghosts," and melanin composition in Cryptococcus neoformans

Y Wang, P Aisen, A Casadevall - Infection and immunity, 1996 - Am Soc Microbiol
… (iii) disruption of melanin by NaOCl, (iv) strain differences in melanin content after growth in
… in the melanin produced after growth in various substrates. Cryptococcus neoformans is an …

Capsule and melanin synthesis in Cryptococcus neoformans

DC McFadden, A Casadevall - Medical Mycology, 2001 - Taylor & Francis
… Down-regulation of the afferent phase of T cell-mediated pulmonary in ammation and
immunity by a high melanin-producing strain of Cryptococcus neoformans. J Immunol 1995; 155: …

Regulation of melanin production by Cryptococcus neoformans

TA Nurudeen, DG Ahearn - Journal of clinical Microbiology, 1979 - Am Soc Microbiol
… , the agents of cryptococcosis, produced melanin-like pigments … Cryptococcus neoformans
within a 72-h incubation period; false-negative reactions can occur. Cryptococcus neoformans

Encapsulation and melanin formation as indicators of virulence in Cryptococcus neoformans

KJ Kwon-Chung, JC Rhodes - Infection and immunity, 1986 - Am Soc Microbiol
… These mutants produced melanin at 30C but not at 37C. One of … Melanin-lacking mutants of
Cryptococcus neoformans and … of catecholamines in Cryptococcus neoformans. J. Bacteriol. …

Melanin-lacking mutants of Cryptococcus neoformans and their virulence for mice

KJ Kwon-Chung, I Polacheck, TJ Popkin - Journal of bacteriology, 1982 - Am Soc Microbiol
… A double mutant of Cryptococcus neoformans which lacked the ability to produce melanin
(… Cryptococcus neoformans produces infection in both human and animals. Any part of the …

Cryptococcus neoformans Can Utilize the Bacterial Melanin Precursor Homogentisic Acid for Fungal Melanogenesis

S Frases, A Salazar, E Dadachova… - Applied and …, 2007 - Am Soc Microbiol
… , we analyzed the effect of homogentisic acid on pigment production in C. neoformans,
since this substrate produces melanin pigment in a wide variety of organisms (9). Growth of C. …

An alternative method for the analysis of melanin production in Cryptococcus neoformans sensu lato and Cryptococcus gattii sensu lato

RSN Brilhante, JDA España, LP de Alencar… - Mycoses, 2017 - Wiley Online Library
… an alternative method for the production and indirect quantification of melanin in C. … differences
in melanin production were observed between C. neoformans sensu stricto (VNI), C. gattii …

Fungistatic Activity of Kojic Acid Against Human Pathogenic Fungi and Inhibition of Melanin-production in Cryptococcus neoformans

HY Chee, EH Lee - Mycobiology, 2003 - Taylor & Francis
melanin production of C. neoformans as well as its susceptibility against antifungal agent. …
treatment of kojic acid inhibit melanin production and give a chance to reduce the virulence of …

Novel gene functions required for melanization of the human pathogen Cryptococcus neoformans

FJ Walton, A Idnurm, J Heitman - Molecular microbiology, 2005 - Wiley Online Library
… organisms, including C. neoformans, the unrelated L-DOPA-melanin production pathway is
… In this study, we aimed to determine new molecular components for melanin production in …