… if downstream consequences of defective mRNA decay that we observed in the C.
neoformans ccr4Δ mutant may also occur in the non-pathogen. Notably, C. amylolentus is an …

… of subsets of functionally related mRNAs in response to stressors relevant to pathogenesis,
… Thus, for C. neoformans, host adaptation requires mRNA decay to mediate rapid …

… and was determined to significantly affect the ability of C. neoformans to adapt to stress
induced by a shift to 37C.6, 7 The conventional mRNA degradation pathway is initiated by poly(A)…

… This could result in plasmids that are variably expressed and thus have different degrees
of efficacy in mediating mRNA degradation. Addition of telomeric sequences to the interfering …

… The pathogenic fungus Cryptococcus neoformans must adapt to glucose-limited conditions
… ribosome biogenesis and translation by modulating mRNA decay through a balance of PKA …

… mRNA, as well as RNA-binding proteins, regulate morphology and virulence by controlling
mRNA degradation … This review summarizes the mRNA degradation pathways and how they …

… is the nonsense-mediated mRNA decay (NMD) pathway, which upon translation recognizes
and degrades mRNAs that … Thus, we expected most of the alternative mRNA molecules in C. …

… mRNA. In addition, our results demonstrated that the essential nucleases Rrp44p and
Xrn2p are implicated in the degradation of mRNA transcribed from an intronless allele in C. …

… to growth at 37C through HXL1 mRNA decay. We postulate that by regulating the fate of
HXL1 mRNA, Puf4 is able to modulate UPR kinetics in C. neoformans, controlling both the …

… The pathogenic fungus Cryptococcus neoformans must overcome multiple stressors to …
Given the role of Ccr4 in catalysing the first and rate limiting step in conventional mRNA decay (…