Transcriptional regulation by protein kinase A in Cryptococcus neoformans

G Hu, BR Steen, T Lian, AP Sham, N Tam… - PLoS …, 2007 - journals.plos.org
protein kinase A (PKA) is known to reduce capsule size and attenuate virulence in the
fungal pathogen Cryptococcus neoformans. … expression of ribosomal protein genes, genes …

Interaction of Cryptococcus neoformans Rim101 and Protein Kinase A Regulates Capsule

TR O'Meara, D Norton, MS Price, C Hay… - PLoS …, 2010 - journals.plos.org
Cryptococcus neoformans is a prevalent human fungal pathogen that must survive within
various tissues … Cryptococcus neoformans strains used in this study are listed in Table 1. All C. …

The cAMP/Protein Kinase A Pathway Regulates Virulence and Adaptation to Host Conditions in Cryptococcus neoformans

M Caza, JW Kronstad - Frontiers in cellular and infection microbiology, 2019 - frontiersin.org
… For instance, protein kinase A (PKA) in the human pathogen Cryptococcus neoformans plays
a … Saccharomyces cerevisiae to provide a foundation for understanding the pathway in C. …

Cyclic AMP-dependent protein kinase controls virulence of the fungal pathogen Cryptococcus neoformans

CA D'Souza, JA Alspaugh, C Yue… - … and cellular biology, 2001 - Am Soc Microbiol
Cryptococcus neoformans is an opportunistic fungal … (cAMP)-dependent protein kinase
catalytic subunit was identified … The PKR1 gene encoding the protein kinase A (PKA) regulatory …

The cAMP/Protein Kinase A Pathway and Virulence in Cryptococcus neoformans

JW Kronstad, G Hu, J Choi - Mycobiology, 2011 - Taylor & Francis
… One of these pathways, the cAMP/protein kinase A (PKA) pathway, has been characterized
… /PKA pathway in the basidiomycete pathogen Cryptococcus neoformans. This fungus is the …

Cross talk between the cell wall integrity and cyclic AMP/protein kinase A pathways in Cryptococcus neoformans

MJ Donlin, R Upadhya, KJ Gerik, W Lam… - MBio, 2014 - Am Soc Microbiol
Cryptococcus neoformans is a fungal pathogen of immunocompromised people that
causes … The fungal cell wall is essential to viability and pathogenesis of C. neoformans, and …

Analysis of the protein kinase A-regulated proteome of Cryptococcus neoformans identifies a role for the ubiquitin-proteasome pathway in capsule formation

JMH Geddes, M Caza, D Croll, N Stoynov, LJ Foster… - MBio, 2016 - Am Soc Microbiol
… fungal pathogen Cryptococcus neoformans causes cryptococcal meningitis in … C, to produce
a polysaccharide capsule and melanin, and to secrete extracellular enzymes and proteins

Signalling pathways in the pathogenesis of Cryptococcus

L Kozubowski, SC Lee, J Heitman - Cellular microbiology, 2009 - Wiley Online Library
… the protein kinase A/cyclic AMP (cAMP), protein kinase C (PKC)/mitogen-activated protein
kinase (… The human pathogenic basidiomycetous fungus Cryptococcus neoformans deploys …

Ssk2 Mitogen-Activated Protein Kinase Kinase Kinase Governs Divergent Patterns of the Stress-Activated Hog1 Signaling Pathway in Cryptococcus neoformans

YS Bahn, S Geunes-Boyer, J Heitman - Eukaryotic cell, 2007 - Am Soc Microbiol
… The stress-activated p38/Hog1 mitogen-activated protein kinase (MAPK) pathway is …
virulence factors in a majority of clinical Cryptococcus neoformans serotype A and D strains. Here, …

Systematic functional analysis of kinases in the fungal pathogen Cryptococcus neoformans

KT Lee, YS So, DH Yang, KW Jung, J Choi… - Nature …, 2016 - nature.com
neoformans protein kinases based on these criteria, we queried their amino acid
sequences in the Kinomer v.1.0 database (http://www.compbio.dundee.ac.uk/kinomer/), which …