… follow-up comparing PFO closure plus long-term antiplatelet therapy with best medical
therapy before we know whether PFO closure is beneficial in cryptogenic stroke in the long term. …

… In conclusion, our study shows that transcatheter closure is associated with a significant
reduction in the risk of stroke compared to medical management at the expense of an increased …

… Based on current evidence, it is premature to conclude that transcatheter closure of a PFO
is futile in cryptogenic stroke, and we therefore advocate continued randomization of future …

… favors transcatheter closure of … transcatheter closure of PFO using the APFOO versus dual
antiplatelet therapy with clopidogrel and aspirin for secondary prevention of cryptogenic stroke…

… source for cryptogenic strokes. Percutaneous PFO closure to reduce the recurrence of stroke
… The aim of this study is to assess whether PFO closure in patients with cryptogenic stroke is …

… that in patients with cryptogenic stroke and a PFO, transcatheter closure is superior to
medical therapy for secondary prevention of stroke. All included trials suggested that closure is …

… with cryptogenic cerebral infarcts1-4. Finally, the recurrence rate of cryptogenic stroke is …
These facts suggest a strong role of a PFO in cryptogenic stroke. A large PFO8,9 and the …

… after transcatheter closure of patent foramen ovale (PFO) in cryptogenic stroke or TIA.
Methods. We retrospectively reviewed PFO closure procedures for the secondary prevention of …

… transcatheter PFO closure compared with medical therapy in patients who presented with
cryptogenic stroke … We identified clinical predictors of recurrent ischemic stroke or TIA during 2 …

… The present meta-analysis including all the currently available RCTs of transcatheter closure
of PFO versus medical therapy after cryptogenic stroke suggests that PFO closure might be …