Cryptosporidium parvum regulation of human epithelial cell gene expression
M Deng, CA Lancto, MS Abrahamsen - International journal for …, 2004 - Elsevier
… To identify genes with significantly altered expression, a series of statistical analyses (…
for ratio of expression levels 1.80 and 0.55 were used to filter genes with expression level fold …
for ratio of expression levels 1.80 and 0.55 were used to filter genes with expression level fold …
[HTML][HTML] Genetic modification of the diarrhoeal pathogen Cryptosporidium parvum
… We note that Nluc expression remains stable when parasites are propagated in mice in the
… system for cryptosporidiosis. They genetically modify Cryptosporidium parvum by optimizing …
… system for cryptosporidiosis. They genetically modify Cryptosporidium parvum by optimizing …
Cryptosporidium parvum disrupts intestinal epithelial barrier function via altering expression of key tight junction and adherens junction proteins
A Kumar, I Chatterjee, AN Anbazhagan… - Cellular …, 2018 - Wiley Online Library
… ), these changes did not involve downregulation of expression of TJ/AJ proteins. Overall,
our results could suggest that decreased expression of specific AJC proteins in mouse ileum in …
our results could suggest that decreased expression of specific AJC proteins in mouse ileum in …
Innate immune responses against Cryptosporidium parvum infection
V McDonald, DS Korbel, FM Barakat… - Parasite …, 2013 - Wiley Online Library
… Infection of epithelial cells alters expression of hundreds of hosts cell genes, many of them
associated with apoptosis 47. In studies with epithelial cell lines a proportion of cells was …
associated with apoptosis 47. In studies with epithelial cell lines a proportion of cells was …
Cryptosporidium parvum: radiation-induced alteration of the oocyst proteome
SU Lee, M Joung, T Nam, WY Park, YH Ji… - Experimental …, 2011 - Elsevier
… parvum proteins with altered expression patterns that resulted as a consequence of a 10-kGy
dose of γ-radiation, the oocyst proteome was subjected to 2-DE. Separated proteins were …
dose of γ-radiation, the oocyst proteome was subjected to 2-DE. Separated proteins were …
Biphasic Modulation of Apoptotic Pathways in Cryptosporidium parvum-Infected Human Intestinal Epithelial Cells
J Liu, M Deng, CA Lancto, MS Abrahamsen… - Infection and …, 2009 - Am Soc Microbiol
… parvum infection, 10 genes were apoptosis regulators, including general apoptosis inducer
… An additional 41 transcripts with altered expression patterns during C. parvum infection …
… An additional 41 transcripts with altered expression patterns during C. parvum infection …
[HTML][HTML] The Cryptosporidium Parvum Transcriptome during In Vitro Development
MJ Mauzy, S Enomoto, CA Lancto, MS Abrahamsen… - PloS one, 2012 - journals.plos.org
… , but to delineate patterns of gene expression we focused on the relative change of gene …
At 48 hr we observed a spike in expression of seven Cryptosporidium related genes, including …
At 48 hr we observed a spike in expression of seven Cryptosporidium related genes, including …
Nuclear delivery of parasite Cdg2_FLc_0220 RNA transcript to epithelial cells during Cryptosporidium parvum infection modulates host gene transcription
GH Zhao, AY Gong, Y Wang, XT Zhang, M Li… - Veterinary …, 2018 - Elsevier
… We found that alterations in host gene expression profile following C. parvum infection
were … The total numbers of genes whose expression is significantly altered after infection or …
were … The total numbers of genes whose expression is significantly altered after infection or …
Host intestinal epithelial response to Cryptosporidium parvum
M Deng, MS Rutherford, MS Abrahamsen - Advanced drug delivery reviews, 2004 - Elsevier
… on Cryptosporidium has focused on the identification and characterization of antigens expressed
on … In addition to altering epithelial chloride and fluid secretion, increased production of …
on … In addition to altering epithelial chloride and fluid secretion, increased production of …
RNA-Seq analysis during the life cycle of Cryptosporidium parvum reveals significant differential gene expression between proliferating stages in the intestine and …
C Lippuner, C Ramakrishnan, WU Basso… - International journal for …, 2018 - Elsevier
… -Seq to compare gene expression in sporozoites and intracellular stages of C. parvum to
identify genes … grown in vitro (517 genes with FDR <0.01, absolute log2 fold change >1). (C, D) …
identify genes … grown in vitro (517 genes with FDR <0.01, absolute log2 fold change >1). (C, D) …
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- cryptosporidium parvum infection
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- intestinal epithelial barrier function altering expression
- junction proteins altering expression