… for the analysis of liquid biopsy samples from cancer patients. This review will focus on the
new perspectives and challenges of cfDNA analysis from mutation detection in patients with …

… mutation detection in ctDNA and provide an overview of the characteristics of ctDNA, detection
methods for ctDNA … followed to ensure we get the right information from ctDNA analysis. …

… detection of tumor genetic aberrations. Recent improvements in the sensitivity, specificity, and
feasibility of ctDNA detection … studies using ctDNA analysis in early lung cancer detection, …

… We then sought to analyze the impact of treatment on RAS mutation detection in plasma. No
… Because ctDNA analysis has the capacity to reflect tumor load [2], we examined the utility of …

… In each cohort, we compared the mutation detection rate in cfDNA for mutations with …
rationale for the selection of ctDNA markers for tumor-informed ctDNA analysis. Furthermore, it pro…

… In this study, we present a multiplexed SCODA mutation detection assay for measuring
plasma ctDNA, which has been characterized here for its ability to assess a panel of 46 …

… mutation.11, 12 Analysis of tumor tissue biopsy material is considered the conventional standard
method for mutation detection… DNA is extracted and analyzed to detect EGFR mutations. …

… Detection of this ctDNA offers a complementary method or possibly an alternative to mutation
detection … a high degree of concordance between variants found in tissue and blood ctDNA.…

… and ctDNA increased the sensitivity for EGFR mutation detection … of ctDNA and poses
challenges for mutation detection on … but not identified as such by ctDNA analysis alone. The data …

… circulating tumor DNA (ctDNA) with a nine gene, 96 mutation … was analyzed for detection
of low levels ctDNA using a blood … Subjects with detectable copies of ctDNA were asked to …