Influence of follicular fluid and cumulus cells on oocyte quality: clinical implications
MG Da Broi, VSI Giorgi, F Wang, DL Keefe… - Journal of assisted …, 2018 - Springer
… An oocyte is considered competent when it is able to … the acquisition of oocyte competence
and protect the oocyte from … and their functional integrity) affect oocyte quality in the context of …
and protect the oocyte from … and their functional integrity) affect oocyte quality in the context of …
[HTML][HTML] Oocyte environment: follicular fluid and cumulus cells are critical for oocyte health
DA Dumesic, DR Meldrum, MG Katz-Jaffe, RL Krisher… - Fertility and sterility, 2015 - Elsevier
… cumulus cell genes as markers of oocyte quality include COX2, GREM1, HAS2, and PTX3
108, 109. Cumulus cells from oocytes developing into high-quality … cumulus cells from oocytes …
108, 109. Cumulus cells from oocytes developing into high-quality … cumulus cells from oocytes …
Redox biology of human cumulus cells: basic concepts, impact on oocyte quality, and potential clinical use
L von Mengden, F Klamt, J Smitz - Antioxidants & redox signaling, 2020 - liebertpub.com
… Cumulus cells (CCs) play essential roles in the oocyte's growth and maturation processes.
For example, they protect the oocyte … the oocyte is incapable of metabolizing (7). In the follicle, …
For example, they protect the oocyte … the oocyte is incapable of metabolizing (7). In the follicle, …
Oocyte-secreted factors: regulators of cumulus cell function and oocyte quality
RB Gilchrist, M Lane… - Human reproduction …, 2008 - academic.oup.com
… role and the cumulus cells (CCs), which form an intimate association with the oocyte. CCs
… gap junctions at their tips with the oocyte, forming an elaborate structure called the cumulus–…
… gap junctions at their tips with the oocyte, forming an elaborate structure called the cumulus–…
[HTML][HTML] Cumulus and granulosa cell markers of oocyte and embryo quality
… Cumulus cells play a vital role in regulating oocyte maturation 32, 33. During the meiotic
arrest, cyclic guanosine monophosphate (cGMP) from cumulus cells passes into the oocyte …
arrest, cyclic guanosine monophosphate (cGMP) from cumulus cells passes into the oocyte …
The human oocyte and cumulus cells relationship: new insights from the cumulus cell transcriptome
… We also explore the potential for the gene expression data to reveal novel biomarkers of
oocyte quality and assist the optimization of assisted reproductive technologies. …
oocyte quality and assist the optimization of assisted reproductive technologies. …
Mechanistic insights into the reduced developmental capacity of in vitro matured oocytes and importance of cumulus cells in oocyte quality determination
A Li, F Wang, L Li, LH Fan, TG Meng… - Journal of Cellular …, 2020 - Wiley Online Library
… The objective of our experiments was to determine up to what degree oocyte IVM will
affect mitochondrial function and how the cumulus cells affect oocyte quality as indicated by …
affect mitochondrial function and how the cumulus cells affect oocyte quality as indicated by …
Evaluation of telomere length in cumulus cells as a potential biomarker of oocyte and embryo quality†.
EH Cheng, SU Chen, TH Lee, YP Pai… - Human …, 2013 - search.ebscohost.com
… Our results suggest that the telomere length in cumulus cells is related to oocyte quality
and embryo development. To select the best embryo is very important for clinical infertility …
and embryo development. To select the best embryo is very important for clinical infertility …
PCOS and role of cumulus gene expression in assessing oocytes quality
… on these oocytes may directly impair the quality and affect … especially in the cumulus cells
oocytes complex will help to … expression in cumulus cells with regards to oocytes quality in both …
oocytes complex will help to … expression in cumulus cells with regards to oocytes quality in both …
Nurturing the egg: the essential connection between cumulus cells and the oocyte
C Robert - Reproduction, Fertility and Development, 2021 - CSIRO Publishing
… The intimate relationship between the oocyte and the surrounding cumulus cells is essential
to the development of a high-quality oocyte capable of resuming meiosis, being fertilised …
to the development of a high-quality oocyte capable of resuming meiosis, being fertilised …
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