Developmental, cytogenetic and epigenetic consequences of removing complex proteins and adding melatonin during in vitro maturation of bovine oocytes

DAR Tutt, G Guven-Ates, WY Kwong… - Frontiers in …, 2023 - frontiersin.org
Cumulus-oocyte complexes (COCs) utilized in this study were retrieved from four cycles of
… -derived factors such as GDF9 and BMP15 in regulating cholesterol biosynthesis in cumulus

The role of melatonin as an antioxidant in the follicle

H Tamura, A Takasaki, T Taketani, M Tanabe… - Journal of ovarian …, 2012 - Springer
Melatonin, a hormone mainly synthesized in the pineal gland, has multiple effects … melatonin
and 8-OHdG, suggesting that melatonin in the follicle diffuses into the cumulus and oocytes

Melatonin improves meiosis maturation against diazinon exposure in mouse oocytes

Y Gai, MY Zhang, PY Ji, RJ You, ZJ Ge, W Shen… - Life Sciences, 2022 - Elsevier
… the developmental potential of oocyte [12]. In this study, cumulus oocyte complexes (COCs) …
One main site of melatonin synthesis is mitochondrion in oocytes [42]. With the addition of …

Melatonin, clock genes, and mammalian reproduction: what is the link?

A Brzezinski, S Rai, A Purohit… - International journal of …, 2021 - mdpi.com
… The circadian rhythm of melatonin synthesis in the pineal gland is involved in the regulation
of mammalian (including humans) reproduction [1,2,3,4]. In 1963, Wurtman et al. [5] first …

Does supplementation of in-vitro culture medium with melatonin improve IVF outcome in PCOS?

MK Kim, EA Park, HJ Kim, WY Choi, JH Cho… - Reproductive …, 2013 - Elsevier
Melatonin concentrations in the culture media of granulosa cells (GC) or cumulus-oocyte-complexes
To confirm that the enzymic pathways for melatonin synthesis are present in GC, …

Stimulatory effects of melatonin on porcine in vitro maturation are mediated by MT2 receptor

S Lee, JX Jin, A Taweechaipaisankul, GA Kim… - International journal of …, 2018 - mdpi.com
… exists in follicular fluid [8], and that it could be synthesized by the oocytes, as well as that …
of melatonin on porcine cumulus oocyte complexes (COCs) through melatonin membrane …

Melatonin delivery by nanocapsules during in vitro bovine oocyte maturation decreased the reactive oxygen species of oocytes and embryos

MH Remião, CG Lucas, WB Domingues, T Silveira… - Reproductive …, 2016 - Elsevier
… , melatonin-loaded LNC were synthesized using … cumulus-oocyte complexes (COCs). Only
the COCs with homogeneous cytoplasm and a minimum of three layers of compact cumulus

[PDF][PDF] Effect of melatonin supplementation to the maturation media on in vitro cumulus cells expansion and nuclear maturation rates of buffalo oocytes

SM Shamiah, AA Fathy, EA Abd-Allah, WM Nagy - Animal Biotechnology - researchgate.net
… of melatonin synthesis in the cumulus oocyte complexes and its role in enhancing oocyte
maturation in vitro in cattle. Molecular Reproduction & Development: DOI 10.1002/mrd.21295 …

Melatonin Receptor 2 Promotes Lipid Metabolism of Cumulus-oocyte Complexes via the cAMP/PKA Pathway

JX Jin, HD Cui, CQ Jiang, ZC Qi, Y Bian, JH Liu… - 2021 - researchsquare.com
… demonstrated that melatonin up-regulated lipid metabolism during oocyte maturation. …
Melatonin in uences the sonic hedgehog signaling pathway in porcine cumulus oocyte complexes

Essential actions of melatonin in protecting the ovary from oxidative damage

MHC Cruz, CLV Leal, JF Cruz, DX Tan, RJ Reiter - Theriogenology, 2014 - Elsevier
melatonin concentrations in follicular fluid and oocyte quality … develop and provide a competent
oocyte for fertilization. The … Melatonin is an indoleamine synthesized from tryptophan via …