Melatonin abrogates the anti-developmental effect of the AKT inhibitor SH6 in bovine oocytes and embryos

M El Sheikh, A Mesalam, AA Mesalam… - International journal of …, 2019 - mdpi.com
… Notably, class I cumulus oocyte complexes (COCs), with five or more layers of cumulus cells
… cells [43] in addition to the ability of oocyte itself to synthesize this multitasking molecule …

Role of melatonin on production and preservation of gametes and embryos: a brief review

MHC Cruz, CLV Leal, JF da Cruz, DX Tan… - Animal reproduction …, 2014 - Elsevier
… The presence of serotonin in granulosa cells and oocytes suggests that melatonin synthesis
… about the involvement of melatonin in cellular protection of the cumulus-oocyte complexes. …

Melatonin enhances the developmental potential of immature oocytes from older reproductive-aged women by improving mitochondrial function

D Yang, Y Mu, J Wang, W Zou, H Zou, H Yang… - Heliyon, 2023 - cell.com
… Following hCG injection, transvaginal ultrasound-guided cumulus-oocyte complexes … corona
cumulus complexes of the oocytes were collected. Subsequently, these cumulus complexes

Melatonin attenuates postovulatory oocyte dysfunction by regulating SIRT1 expression

Q Yang, S Dai, X Luo, J Zhu, F Li, J Liu, G Yao… - …, 2018 - rep.bioscientifica.com
… the oocytes were treated with the SIRT1 activator SRT1720. In conclusion, our data strongly
indicate that melatonin delays postovulatory mouse oocyte … The cumulus-oocyte complexes (…

Effect of melatonin on exosomal dynamics in bovine cumulus cells

M Pournaghi, R Khodavirdilou, MAE Saadatlou… - Process …, 2021 - Elsevier
… the effects of melatonin were investigated on the exosome release from bovine cumulus cells
… The effect of melatonin on cell viability was studied using an MTT assay. The expression of …

Melatonin impact on in vitro development of mouse preantral follicles and oocyte maturation

M Nabiuni, R Ganji, M Bahadori - Anatomical Sciences Journal, 2013 - anatomyjournal.ir
… it has been shown that melatonin in the culture medium did not improve cumulusmelatonin
endocrine message in mammals: a review of the complex regulation of melatonin synthesis

Melatonin‐induced increase of lipid droplets accumulation and in vitro maturation in porcine oocytes is mediated by mitochondrial quiescence

B He, C Yin, Y Gong, J Liu, H Guo… - Journal of cellular …, 2018 - Wiley Online Library
… Briefly, cumulus-oocyte complexes (COCs) were aspirated … ATP synthesis may be activated
in melatonin-treated oocytesmelatonin-treated cumulus cells than control. It suggests that …

Mitochondria-synthesize melatonin to improve the quality and in vitro maturation as well as the embryonic development of porcine oocytes

T Zhu, L Wang, X Ma, G Li, Y Fu, P Ji, L Zhang, G Liu - 2024 - researchsquare.com
… mitochondria isolated from cumulus cells or oocytes both can release melatonin to the …
endocrine message in mammals: a review of the complex regulation of melatonin synthesis

Melatonin exists in porcine follicular fluid and improves in vitro maturation and parthenogenetic development of porcine oocytes

JM Shi, XZ Tian, GB Zhou, L Wang… - Journal of pineal …, 2009 - Wiley Online Library
Cumulus oocyte complexes (COC) were aspirated from … COC with intact compact cumulus
layers were then selected and … way of MPF synthesis promotion was regulated by melatonin

Melatonin receptors: A key mediator in animal reproduction

Y Gao, S Zhao, Y Zhang, Q Zhang - Veterinary Sciences, 2022 - mdpi.com
Melatonin exerts beneficial actions mainly via binding with G-… Melatonin receptors are
crucial for mediating animal reproduction. This paper reviews the characteristics of melatonin