Mitochondria-synthesize melatonin to improve the quality and in vitro maturation as well as the embryonic development of porcine oocytes

T Zhu, L Wang, X Ma, G Li, Y Fu, P Ji, L Zhang, G Liu - 2024 - researchsquare.com
… mitochondria isolated from cumulus cells or oocytes both can release melatonin to the …
endocrine message in mammals: a review of the complex regulation of melatonin synthesis

[HTML][HTML] Melatonin decreases excessive polyspermy for single oocyte in pigs through the MT2 receptor

JT Sun, JH Liu, L Zhao, HY Chen, RF Wang, YJ Li… - Scientific Reports, 2024 - nature.com
… The cumulus-oocyte complexes (COCs) were washed with 10 mM HEPES-buffered TCM199
(Invitrogen, Carlsbad, CA, USA) containing 2 mM of sodium bicarbonate, 5 mM sodium …

Melatonin protects against Mdivi-1-induced abnormal spindle assembly and mitochondrial superoxide production during porcine oocyte maturation

SG Yang, SY Joe, JW Bae, GD Heo, HJ Park… - Frontiers in cell and …, 2021 - frontiersin.org
… Immature cumulusoocyte complexes (COCs) were aspirated … first time, porcine oocyte
melatonin production or synthesis was … for melatonin-synthesizing enzymes by Mdivi-1 in porcine …

Melatonin exists in porcine follicular fluid and improves in vitro maturation and parthenogenetic development of porcine oocytes

JM Shi, XZ Tian, GB Zhou, L Wang… - Journal of pineal …, 2009 - Wiley Online Library
Cumulus oocyte complexes (COC) were aspirated from … COC with intact compact cumulus
layers were then selected and … way of MPF synthesis promotion was regulated by melatonin

Melatonin receptors: A key mediator in animal reproduction

Y Gao, S Zhao, Y Zhang, Q Zhang - Veterinary Sciences, 2022 - mdpi.com
Melatonin exerts beneficial actions mainly via binding with G-… Melatonin receptors are
crucial for mediating animal reproduction. This paper reviews the characteristics of melatonin

Protective effects of melatonin on the in vitro developmental competence of bovine oocytes

Y Pang, S Zhao, Y Sun, X Jiang, H Hao… - Animal Science …, 2018 - Wiley Online Library
Cumulus-oocyte complexes (COCs) from follicles ranging from 2–6 mm in diameter were …
Previously, some literatures have reported that melatonin can be synthesized in the follicular …

[PDF][PDF] Melatonin Impact on In Vitro Development of Mouse Preantral Follicles and Oocyte Maturation

M Bahadori - Evalauation of Laminin Expression during Mouse …, 2013 - researchgate.net
… it has been shown that melatonin in the culture medium did not improve cumulusmelatonin
endocrine message in mammals: a review of the complex regulation of melatonin synthesis

Effect and possible mechanisms of melatonin treatment on the quality and developmental potential of aged bovine oocytes

S Liang, J Guo, JW Choi, NH Kim… - … Fertility and Development, 2017 - CSIRO Publishing
Cumulusoocyte complexes (COCs) where an oocyte was surrounded by a minimum of
three cumulus cells were selected for culture. The IVM procedures were performed according to …

Effect of melatonin treatment on developmental potential of somatic cell nuclear-transferred mouse oocytes in vitro

M Salehi, Y Kato, Y Tsunoda - Zygote, 2014 - cambridge.org
… Females were sacrificed at 13 to 14 h after injection of hCG and cumulusoocyte complexes
… , cumulus-denuded oocytes were collected and washed in FHM. Groups of oocytes were …

[HTML][HTML] Melatonin in maturation media fails to improve oocyte maturation, embryo development rates and DNA damage of bovine embryos

L Takada, A Martins Junior, GZ Mingoti… - Scientia …, 2010 - SciELO Brasil
… of melatonin during in vitro maturation on DNA damage of resulting embryos. This can possibly
be explained by the fact that melatonin is only acting locally in cumulus-oocyte complexes