Genetic associations of the interleukin locus at 1q32. 1 with clinical outcomes of cutaneous melanoma

J Rendleman, M Vogelsang, A Bapodra… - Journal of medical …, 2015 - jmg.bmj.com
… In conclusion, our study provides strong support for a role of the interleukin locus at 1q32.1
in the modulation of melanoma survival. We provide evidence for a novel association with OS …

Distal and proximal interleukin (IL)-10 promoter polymorphisms associated with risk of cutaneous melanoma development: a case–control study

N Schoof, F von Bonin, IR Koenig, R Mössner… - Genes & …, 2009 - nature.com
… The analysis of respective haplotypes showed a strong linkage of the loci and a … risk to
develop cutaneous melanoma, if corrected for the phenotypic risk factors skin type and number of …

The expression quantitative trait loci in immune pathways and their effect on cutaneous melanoma prognosis

M Vogelsang, CN Martinez, J Rendleman… - Clinical Cancer …, 2016 - AACR
… This study comprises a total of 1,221 patients with cutaneous melanoma (stage I to III) of
self-reported European descent who were treated at the New York University Langone Medical …

[HTML][HTML] Metastatic Lesions with and without Interleukin-18–Dependent Genes in Advanced-Stage Melanoma Patients

O Crende, M Sabatino, M Valcárcel, T Carrascal… - The American Journal of …, 2013 - Elsevier
… Total RNA from both melanoma cells and primary cutaneous melanoma lesions was used
to generate first-strand cDNA with the Multiscribe Reverse Transcriptase (Applied Biosystems, …

HLA‐DQB1*0301 association with increased cutaneous melanoma risk

JE Lee, JD Reveille, MI Ross… - International journal of …, 1994 - Wiley Online Library
… oligotyping, polymerase chain reaction (PCR) is used to amplify genomic DNA class I1
genes by employing locusspecific class I1 amplification primers. The amplified product is then …

Complete regression of subcutaneous and cutaneous metastatic melanoma with high-dose intralesional interleukin 2 in combination with topical imiquimod and …

MS Garcia, Y Ono, SR Martinez, SL Chen… - Melanoma …, 2011 - journals.lww.com
cutaneous melanoma metastases in January 2010. His dermatologic history was significant
for three primary cutaneous melanomas … their major histocompatibility complex loci may still …

Germline determinants of clinical outcome of cutaneous melanoma

M Vogelsang, M Wilson… - Pigment cell & melanoma …, 2016 - Wiley Online Library
… , for example interleukin locus at chromosome 1q32 … personalized germline markers in
melanoma prognostication will need … more important melanoma prognostic genomic loci. Among …

The genetic variants in interleukin locus at 1q32. 1 as markers of melanoma survival.

J Rendleman, C Adaniel, E Kern, NH Fleming… - 2014 - ascopubs.org
… genetic risk variants in an interleukin locus at 1q32.1 with melanoma outcomes (rs3024493), …
study strongly suggests that germline variants in the interleukin locus at 1q32.1 should be …

Variant of TYR and Autoimmunity Susceptibility Loci in Generalized Vitiligo

Y Jin, SA Birlea, PR Fain, K Gowan… - … England Journal of …, 2010 - Mass Medical Soc
… To identify generalized vitiligo susceptibility loci, we conducted a genomewide association
study. We genotyped 579,146 single-nucleotide polymorphisms (SNPs) in 1514 patients with …

Antitumor effect by interleukin-11 receptor α-locus chemokine/CCL27, introduced into tumor cells through a recombinant adenovirus vector

JQ Gao, Y Tsuda, K Katayama, T Nakayama… - Cancer research, 2003 - AACR
In this study, we examined antitumor activity of a mouse CC chemokine ILC/CCL27 and a
mouse CX 3 C chemokine fractalkine/CX 3 CL1 in vivo. We generated recombinant …