Promoter methylation of cyclin D2 gene in gastric carcinoma

Y Oshimo, H Nakayama, R Ito… - International …, 2003 - spandidos-publications.com
… expression of cyclin D2 in gastric carcinoma still remains to be … in abnormal expression of
cyclin D2 in gastric carcinoma, we … of cyclin D2 by methylation-specific PCR (MSP) in 34 gastric

Cyclin D2, but not cyclin D1, overexpression closely correlates with gastric cancer progression and prognosis

Y Takano, Y Kato, M Masuda, Y Ohshima… - The Journal of …, 1999 - Wiley Online Library
… of another G1 cyclin.We have therefore considered the possibility that the cyclin D2 gene
may play an important role in gastric cancer progression in co-operation with the cyclin E gene. …

Cyclin D2 overexpression and lack of p27 correlate positively and cyclin E inversely with a poor prognosis in gastric cancer cases

Y Takano, Y Kato, PJ van Diest, M Masuda… - The American journal of …, 2000 - Elsevier
cyclin D1 (CCND1), cyclin D2 (CCND2), cyclin E (CCNE), CDK2, and CDK4, in addition to
p27, in 260 gastric cancertumor progression and prognosis. Examination of 20 cases of fresh …

Expression of cyclin genes in human gastric cancer and in first degree relatives

J Yu, S Miehlke, MPA Ebert, D Szokodi… - Chinese medical …, 2002 - mednexus.org
… In conclusion,cyclins D2,D3 and E are highly expressed in gastric cancer patients,and also
in first degree relatives, intestinal metaplasia and atrophic gastritis tissues,as well as H. pylori …

Cyclin D1 and cyclin E2 are differentially expressed in gastric cancer

S Kumari, Puneet, SB Prasad, SS Yadav, M Kumar… - Medical Oncology, 2016 - Springer
… Deregulated expression of these cyclins has been … gastric carcinoma. We aimed to explore
that whether there is differential expression of these cyclins in clinically distinct gastric cancer

Absence of cyclin D2 expression is associated with promoter hypermethylation in gastric cancer

J Yu, WK Leung, MPA Ebert, RWL Leong… - … journal of cancer, 2003 - nature.com
… of the cyclin D2 gene is detected in a subset of gastric cancer. Our results suggest that the
development of a subset of gastric cancer is independent of cyclin D2 expression. Further …

[HTML][HTML] Cyclin D1 overexpression correlates with poor tumor differentiation and prognosis in gastric cancer

YS Shan, HP Hsu, MD Lai, YH Hung… - Oncology …, 2017 - spandidos-publications.com
… In the present study, the expression of the cyclin D1 (CCND1), cyclin D2 (CCND2) and cyclin
D3 (CCND3) genes in gastric cancer patients was explored using the Oncomine database, …

miR-206 inhibits gastric cancer proliferation in part by repressing cyclinD2

L Zhang, X Liu, H Jin, X Guo, L Xia, Z Chen, M Bai… - Cancer letters, 2013 - Elsevier
… Specifically, miR-206 regulates CCND2 transcript and protein levels by binding to its 3′UTR,
further affects the Cyclin D2/CDK4/CDK6 complex formation, resulting in growth inhibition …

Prognostic role of cyclin D2/D3 in multiple human malignant neoplasms: A systematic review and meta‐analysis

Z Ding, R Li, Q Zhang, Y Wang, Y Jiang… - Cancer …, 2019 - Wiley Online Library
… are gastric cancer, NSCLC, colorectal cancer, breast cancer, … role in gastric cancer, whereas
it could also be a tumor … prognostic factor in breast cancer and bladder cancer. These results …

Expression of G1 Phase Cyclins in Human Gastric Cancer and Gastric Mucosa of First-Degree Relatives

S Miehlke, J Yu, M Ebert, D Szokodi, M Vieth… - Digestive diseases and …, 2002 - Springer
… of cyclin D2 has been described in gastric carcinoma, and was … regarding cyclin D3 expression
in gastric cancer are lacking. … cyclins and cyclin E in gastric cancer tissue compared with …