Calcium cycling and signaling in cardiac myocytes
DM Bers - Annu. Rev. Physiol., 2008 - annualreviews.org
… This review focuses on Ca signaling in cardiac myocytes as pertaining to electrophysiology
(including action potentials and arrhythmias), excitation-contraction coupling, modulation of …
(including action potentials and arrhythmias), excitation-contraction coupling, modulation of …
An integrated mechanism of cardiomyocyte nuclear Ca2+ signaling
… Thus, current evidence suggests that, depending on whether a nuclear Ca 2 + transient
arises during an E–C coupling cycle or in response to activation of a receptor on the plasma …
arises during an E–C coupling cycle or in response to activation of a receptor on the plasma …
Phospholamban regulates nuclear Ca2+ stores and inositol 1, 4, 5-trisphosphate mediated nuclear Ca2+ cycling in cardiomyocytes
… it can modulate perinuclear Ca 2+ handling of the cardiomyocytes (CMs). … nuclear Ca 2+
release, we examined whether the nuclear pool of PLB regulates IP 3 -induced nuclear Ca 2+ …
release, we examined whether the nuclear pool of PLB regulates IP 3 -induced nuclear Ca 2+ …
Nuclear calcium in cardiac myocytes
S Ljubojevic, DM Bers - Journal of cardiovascular pharmacology, 2015 - journals.lww.com
… will discuss nuclear Ca 2+ signaling in cardiomyocytes, with … in reliably measuring nuclear
Ca 2+ concentration, [Ca 2+ ] nuc … The Ca 2+ cycle in cardiomyocytes that governs contraction …
Ca 2+ concentration, [Ca 2+ ] nuc … The Ca 2+ cycle in cardiomyocytes that governs contraction …
Calcium signaling and transcriptional regulation in cardiomyocytes
M Dewenter, A von der Lieth, HA Katus… - Circulation …, 2017 - Am Heart Assoc
… In this article, we (1) review cytosolic and nuclear Ca 2+ dynamics in cardiomyocytes with
respect to … In the following, we focus on pathways that link cardiomyocyte Ca 2+ cycling with …
respect to … In the following, we focus on pathways that link cardiomyocyte Ca 2+ cycling with …
Diabetes and the accompanying hyperglycemia impairs cardiomyocyte calcium cycling through increased nuclear O-GlcNAcylation
RJ Clark, PM McDonough, E Swanson, SU Trost… - Journal of biological …, 2003 - ASBMB
… other elements of myocardial Ca 2+ cycling), we examined whether the overall level of O-GlcNAcylation
was altered in nuclear extracts from cardiomyocytes. The monoclonal antibody …
was altered in nuclear extracts from cardiomyocytes. The monoclonal antibody …
Ca2+ Cycling and New Therapeutic Approaches for Heart Failure
AM Lompré, RJ Hajjar, SE Harding, EG Kranias… - Circulation, 2010 - Am Heart Assoc
… + , SERCA2a expression inhibits calcineurin activity and activation of the NFAT (nuclear …
in preclinical testing of targeting Ca 2+ cycling in the failing cardiac myocyte have led to the …
in preclinical testing of targeting Ca 2+ cycling in the failing cardiac myocyte have led to the …
Phospholamban is concentrated in the nuclear envelope of cardiomyocytes and involved in perinuclear/nuclear calcium handling
… outside the SR and possible contributions to Ca 2 + cycling remain unknown. We examined
the … that phosphorylation of PLB increased SERCA Ca 2 + uptake into nuclear Ca 2 + stores. …
the … that phosphorylation of PLB increased SERCA Ca 2 + uptake into nuclear Ca 2 + stores. …
Early Remodeling of Perinuclear Ca2+ Stores and Nucleoplasmic Ca2+ Signaling During the Development of Hypertrophy and Heart Failure
… changes of the nuclear envelope and nuclear Ca 2+ handling in cardiomyocytes as remodeling
… The Ca 2+ cycle in cardiomyocytes that governs contraction and relaxation on a beat-to-…
… The Ca 2+ cycle in cardiomyocytes that governs contraction and relaxation on a beat-to-…
Modulation of sarcoplasmic reticulum Ca2+ cycling in systolic and diastolic heart failure associated with aging
AM Janczewski, EG Lakatta - Heart failure reviews, 2010 - Springer
… Ca 2+ transporting proteins, and functional consequences of these changes at the cardiac
myocyte … age, eg the nuclear binding activity of the transcription factor nuclear factor-κB is …
myocyte … age, eg the nuclear binding activity of the transcription factor nuclear factor-κB is …