… Through screening of yeast transformants expressing candidate CYP genes and in vitro
microsomal reaction, we finally found and confirmed the role of CYP5139G1 playing in GAs …

… In S. cerevisiar, Cypl, the major cytosolic Cyp encoded by the CYPl gene (our nomenclature;
… To further investigate the function of Cyp isoforms, we recently cloned a second Cyp-related …

… Only after chemical carcinogens are activated by metabolizing enzymes, including CYP, can
… the activation of CYPs, and there are three CYP genes which need CPR for functioning in S. …

The present study evaluated the ability of a Saccharomyces cerevisiae expression system
to predict the pharmacokinetic (PK) activity of a calcium channel blocker in patients with …

… We report the analysis of two Saccharomyces cerevisiae cyclophilins, Cpr6 and Cpr7, …
significant amino acid identity with the mammalian cyclophilin CyP-40. Neither CPR6 nor CPR7 is …

… cerevisiae YL-T3 which may facilitate the identification of CYPs involved in post-modification
of lanosterol. After obtaining a functional CYP gene cyp5150l8, we continued the yeast …

… for CYP-encoding genes in order to determine the taxonomic distribution of individual CYP
… The aim of the present study was to conduct a comprehensive survey of CYP genes among …

… The yeast Saccharomyces cerevisiae is an ideal host for heterologous … genes, since this
microorganism … cDNAs coding for CYP 1 A 1, CYP 1 A2 and hmEH have been expressed in S. …

… We confirmed the presence of the CYP3A4 gene by PCR … CYP after exposure DMSO or
indicated doses of MeIQx. The third row is growth curves of cells expressing CYP3A4 or no CYP …

… Because Saccharomyces cerevisiae (budding yeast) does not contain CYPs that … been
useful in determining which human CYPs metabolically activate compounds to form genotoxins. …