… a defective CYP2C19 enzyme function associated with polymorphic CYP2C19 genotypes is
a … correlation between the IPA values and pharmacokinetic parameters of clopidogrel. Taken …

… ] recently reported that the CYP2C19 polymorphism affects the plasma levels of clopidogrel
… 2C19 polymorphism. In this study, we investigated whether the polymorphism of CYP2C19 …

… of OPZ in three different CYP2C19 genotype groups, as well as the pharmacokinetics of OPZ.
… that the pharmacokinetics and pharmacodynamics of OPZ depend on individual CYP2C19 …

… the pharmacokinetics of PPIs are reportedly influenced by CYP2C19 genetic polymorphisms,
our results suggest that ilaprazole is metabolized differently from the CYP2C19-sensitive …

… We hypothesized that loss of function polymorphisms of CYP … a corresponding effect on the
pharmacodynamic response. However, … For CYP2C19, the *2 allele was the only CYP2C19 …

… The significant effects of CYP2C19 polymorphisms on gliclazide pharmacokinetics observed
in this study are consistent with those previously reported for healthy volunteers (21). In the …

… into the molecular genetic basis of the CYP2C19 polymorphism and the enzymology of the
… the pharmacokinetic changes and the resulting pharmacodynamic response to CYP2C19 …

… CYP2C19 activity on the single-dose pharmacokinetics and pharmacodynamics of etizolam.
… Therefore, the clinical significance of CYP2C19 polymorphism in the treatments with these …

… in CYP2C19 activity that produce changes in the pharmacokinetics and pharmacodynamics
… is to review the influence of CYP2C19 genetic polymorphism on the pharmacokinetics/ phar…

… CYP2C19 are highly polymorphic. A number of clinical studies have addressed the impact of
CYP2C9 and CYP2C19 polymorphisms … Pharmacokinetic and pharmacodynamic variation …