[HTML][HTML] The Clinical Impact of the C0/D Ratio and the CYP3A5 Genotype on Outcome in Tacrolimus Treated Kidney Transplant Recipients

T Van Gelder, S Meziyerh, JJ Swen… - Frontiers in …, 2020 - frontiersin.org
… patients after kidney transplantation based … CYP3A5 genotype data were not available. A
French study demonstrated that ethnic origin did not affect outcome after renal transplantation

CYP3A5 polymorphisms in renal transplant recipients: influence on tacrolimus treatment

L Chen, GVR Prasad - Pharmacogenomics and personalized …, 2018 - Taylor & Francis
… suggest that CYP3A5 genotyping is likely more useful if available before kidney transplant.
… recipients similarly demonstrated no relationship between CYP3A5 genotype and renal

Effect of CYP3A5* 3 on kidney transplant recipients treated with tacrolimus: a systematic review and meta-analysis of observational studies

L Rojas, I Neumann, MJ Herrero, V Bosó… - The …, 2015 - nature.com
… nor excluded an effect of the CYP3A5 genotype on the risk of … , the anticipated risk among
CYP3A5 genotype expressers is 7 … among patients with the CYP3A5 expresser genotype (OR=…

CYP3A5 genotype markedly influences the pharmacokinetics of tacrolimus and sirolimus in kidney transplant recipients

L Renders, M Frisman, M Ufer… - Clinical …, 2007 - Wiley Online Library
… the impact of CYP3A5, ABCB1, and ABCC2 genotypes on the dose requirement and
pharmacokinetics of tacrolimus and sirolimus in stable kidney transplant patients receiving trough-…

[HTML][HTML] … controlled trial comparing the efficacy of Cyp3a5 genotype‐based with body‐weight‐based tacrolimus dosing after living donor kidney transplantation

N Shuker, R Bouamar, RHN van Schaik… - … of Transplantation, 2016 - Elsevier
… based on an individual’s CYP3A5 genotype did not lead to a … kidney transplantation , as
compared to a standard, body‐weight‐based dosing approach. In addition, CYP3A5 genotype‐…

Population Pharmacokinetics of Tacrolimus in Adult Kidney Transplant Patients: Impact of: CYP3A5: Genotype on Starting Dose

TK Bergmann, S Hennig, KA Barraclough… - Therapeutic drug …, 2014 - journals.lww.com
… In a recent study by our group, adult kidney transplant recipients who possessed an NR1I2
8055T allele (rs2276707) had higher tacrolimus dose–adjusted exposure compared with …

Influence of the CYP3A5 genotype on tacrolimus pharmacokinetics and pharmacodynamics in young kidney transplant recipients

M Ferraresso, A Tirelli, L Ghio, P Grillo… - … transplantation, 2007 - Wiley Online Library
… As tacrolimus is a substrate of the CYP3A5 gene, the … CYP3A5 polymorphisms on TAC
pharmacokinetics and pharmacodynamics over time in a population of teenage kidney transplant

Personalized tacrolimus doses determined by CYP3A5 genotype for induction and maintenance phases of kidney transplantation

S Vannaprasaht, S Reungjui, D Supanya… - Clinical …, 2013 - Elsevier
… phase throughout the post–kidney transplantation period. The remaining 35 … kidney transplant
recipients in this study of personalized tacrolimus doses determined by cyp3a5 genotype

CYP3A5 genotype is not associated with a higher risk of acute rejection in tacrolimus-treated renal transplant recipients

DA Hesselink, RHN van Schaik… - Pharmacogenetics …, 2008 - journals.lww.com
… to assess the effect of CYP3A5 genotype on (weight-adjusted… of acute rejection after kidney
transplantation. In contrast to … kidney transplant recipients carrying at least one CYP3A5*1 …

CYP3A5 genotype does not influence everolimus in vitro metabolism and clinical pharmacokinetics in renal transplant recipients

N Picard, K Rouguieg-Malki, N Kamar, L Rostaing… - …, 2011 - journals.lww.com
CYP3A5 genotyping might be useful to guide tacrolimus and sirolimus dosing. The aim of
this study was to assess the influence of CYP3A5 … evidence that CYP3A5 genotyping cannot …