… Since identification of the gene responsible for cystic fibrosis (CF) in 1989, significant … the
CF gene, referred to as the CF transmembrane conductance regulator (CFTR), indicate that the …

CYSTIC fibrosis (CF) is a common lethal genetic disease that manifests itself in airway and
other epithelial cells as defective chloride ion absorption and secretion 1,2 , resulting at least …

… Cystic fibrosis is a frequent autosomal recessive disorder that is caused by the … , the cystic
fibrosis transmembrane conductance regulator. The protein is found in the apical membrane of …

The cystic fibrosis transmembrane conductance regulator (CFTR) is an anion channel evolved
from the ATP-binding cassette (ABC) transporter family. In this study, we determined the …

… Cystic fibrosis (CF) is caused by genetic mutations that affect the cystic fibrosis transmembrane
conductance regulator (… membrane of epithelial cells, as well as influencing the gating or …

… CYSTIC fibrosis transmembrane conductance regulator (CFTR) is a plasma membrane CIT
channel … Mutations in CFTR cause cystic fibrosis"" partly through loss of cAMPregulated ClT …

… be responsible for regulation of CFTR … cystic fibrosis; CFTR, cystic tion by PKA and PKC in
CF-2 and find that within CF-2, consensus sites fibrosis transmembrane conductance regulator…

… The cystic fibrosis transmembrane conductance regulator (CFTR) is an epithelial Cl- channel
regulated by cAMPdependent protein kinaseA (1-3). The most common mutation in CF is …

… open apical membrane CL- channels (1, 2). Expression ofwildtype CF transmembrane
conductance regulator (CFTR) (3) in CF epithelia corrects the defect in cAMP-regulated Cl- perme…

… The cystic fibrosis transmembrane conductance regulator (CFTR) was expressed in cultured
cystic fibrosis airway epithelial cells and CIT channel activation assessed in single cells …