Developmental expression of cytochrome P450 enzymes in human liver

J Hakkola, E Tanaka, O Pelkonen - Pharmacology & toxicology, 1998 - Wiley Online Library
… data of the expression of CYPlAl in foetal liver is somewhat conflicting, but it seems probable
that CYPlAl or closely related form is expressed at least to some extent in foetal liver. The …

Zonation of cytochrome P450 expression, drug metabolism and toxicity in liver

KO Lindros - General Pharmacology: The Vascular System, 1997 - Elsevier
… the factors underlying the zonated expression and induction of … of the expression of P450
and other genes in the liver. Our … of how the zonated expression of P450 enzymes in the liver is …

Three patterns of cytochrome P450 gene expression during liver maturation in mice

SN Hart, Y Cui, CD Klaassen, X Zhong - Drug Metabolism and Disposition, 2009 - ASPET
… , the developmental expression of P450 in mouse liver can be … for the expression of P450
during liver maturation. … by members of the cytochrome P450 (P450) superfamily. Humans have …

Cytochrome P450 expression in the liver of food-producing animals

C Ioannides - Current Drug Metabolism, 2006 - ingentaconnect.com
… different aspects of cytochrome P450 function and regulation, and on the factors that can
modify its activity. As a result, our knowledge of the cytochrome P450 expression and function …

Cytochrome P450 gene expression levels in peripheral blood mononuclear cells in comparison with the liver

M Furukawa, M Nishimura, D Ogino, R Chiba… - Cancer …, 2004 - Wiley Online Library
… gene expression in the liver, we measured CYP gene expression levels in PBL and the liver,
… In the present study, CYP4B1 expression was not detectable in the majority of both liver

Zonation of cytochrome P450 isozyme expression and induction in rat liver

R Buehler, KO Lindros, Å Nordling… - European journal of …, 1992 - Wiley Online Library
… patterns of expression of the cytochrome P450 family in the liver. In the normal, uninduced
liver, expression can … None of the P450 isozymes investigated exhibited a distinct periportal …

Cytochrome P450 expression and regulation in the brain

W Kuban, WA Daniel - Drug Metabolism Reviews, 2021 - Taylor & Francis
liver, which also exhibits the highest expression and concentration of transmembrane cytochrome
P450 … Total CYP protein content in the brain is significantly lower compared to the liver

The regulation of liver cytochrome P450 expression and activity by the brain serotonergic system in different experimental models

E Bromek, WA Daniel - Expert Opinion on Drug Metabolism & …, 2021 - Taylor & Francis
Cytochrome P450 (CYP) enzymes are members of the … The expression of liver cytochrome
P450 is under the … -pituitary-liver axis (HPL) affecting growth hormone level/action in the …

[PDF][PDF] Liver‐specific loss of β‐catenin blocks glutamine synthesis pathway activity and cytochrome p450 expression in mice

S Sekine, BYA Lan, M Bedolli, S Feng, M Hebrok - Hepatology, 2006 - Wiley Online Library
… the expression of several cytochrome P450 enzymes also under physiological conditions. We
found that 3 out of 5 cytochrome P450 … In particular, expression of CYP1A2 and CYP2E1 is …

Constitutive expression of hepatic cytochrome P450 genes

FJ Gonzalez, YH Lee - The FASEB journal, 1996 - Wiley Online Library
… cloned from the liver and found to be preferentially expressed … to bind to crs elements in
other more ubiquitously expressed … in tissues other than the liver and kidney, and is expressed